中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Detection of pb2+ in aqueous solution by using a dna-modified microcantilever

文献类型:期刊论文

作者Peng, Rong-Peng1,2,3,4; Xing, Ling-Bao1,2; Wang, Xiao-Jun1,2; Wu, Cheng-juan1,2; Chen, Bin1,2; Ji, Hai-Feng4; Wu, Li-Zhu1,2; Tung, Chen-Ho1,2
刊名Analytical sciences
出版日期2016-10-01
卷号32期号:10页码:1065-1069
关键词Lead ion Detection Microcantilever Sensor Dna
ISSN号0910-6340
通讯作者Chen, bin(chenbin@mail.ipc.ac.cn) ; Ji, hai-feng(hj56@drexel.edu) ; Wu, li-zhu(lzwu@mail.ipc.ac.cn)
英文摘要We developed a novel pb2+-sensor based on a microcantilever that was modified with a specific pb2+-dependent dnazyme molecule. this microcantilever sensor could detect pb2+ sensitively and selectively in an aqueous solution. upon complexation with pb2+, the dnazyme duplex unwinded and formed a g-quadruplex conformation, which led to an increase of repulsion between the dnazyme molecules and a subsequent bending of the microcantilever. this microcantilever sensor could be regenerated, flowing through a strong pb2+ chelator, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. the detection limit of the microcantilever sensor for pb2+ ions is as low as 10(-8) m. the microcantilever sensor also exhibited a high selectivity to pb2+ over other metal ions such as mg2+, fe+, zn2+, ca2+, and cd2+.
WOS关键词GOLD NANOPARTICLES ; LEAD(II) ION ; DNAZYME ; FLUORESCENCE ; SENSOR ; CHEMOSENSORS ; SPECTROMETRY ; ADSORPTION ; PORPHYRINS ; BIOSENSOR
WOS研究方向Chemistry
WOS类目Chemistry, Analytical
语种英语
WOS记录号WOS:000386423300006
出版者JAPAN SOC ANALYTICAL CHEMISTRY
URI标识http://www.irgrid.ac.cn/handle/1471x/2374969
专题中国科学院大学
通讯作者Chen, Bin; Ji, Hai-Feng; Wu, Li-Zhu
作者单位1.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100190, Peoples R China
3.Nanchang Univ, Coll Chem, Nanchang 330031, Jiangxi, Peoples R China
4.Drexel Univ, Dept Chem, Philadelphia, PA 19010 USA
推荐引用方式
GB/T 7714
Peng, Rong-Peng,Xing, Ling-Bao,Wang, Xiao-Jun,et al. Detection of pb2+ in aqueous solution by using a dna-modified microcantilever[J]. Analytical sciences,2016,32(10):1065-1069.
APA Peng, Rong-Peng.,Xing, Ling-Bao.,Wang, Xiao-Jun.,Wu, Cheng-juan.,Chen, Bin.,...&Tung, Chen-Ho.(2016).Detection of pb2+ in aqueous solution by using a dna-modified microcantilever.Analytical sciences,32(10),1065-1069.
MLA Peng, Rong-Peng,et al."Detection of pb2+ in aqueous solution by using a dna-modified microcantilever".Analytical sciences 32.10(2016):1065-1069.

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来源:中国科学院大学

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