Detection of pb2+ in aqueous solution by using a dna-modified microcantilever
文献类型:期刊论文
作者 | Peng, Rong-Peng1,2,3,4; Xing, Ling-Bao1,2; Wang, Xiao-Jun1,2; Wu, Cheng-juan1,2; Chen, Bin1,2; Ji, Hai-Feng4; Wu, Li-Zhu1,2; Tung, Chen-Ho1,2 |
刊名 | Analytical sciences
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出版日期 | 2016-10-01 |
卷号 | 32期号:10页码:1065-1069 |
关键词 | Lead ion Detection Microcantilever Sensor Dna |
ISSN号 | 0910-6340 |
通讯作者 | Chen, bin(chenbin@mail.ipc.ac.cn) ; Ji, hai-feng(hj56@drexel.edu) ; Wu, li-zhu(lzwu@mail.ipc.ac.cn) |
英文摘要 | We developed a novel pb2+-sensor based on a microcantilever that was modified with a specific pb2+-dependent dnazyme molecule. this microcantilever sensor could detect pb2+ sensitively and selectively in an aqueous solution. upon complexation with pb2+, the dnazyme duplex unwinded and formed a g-quadruplex conformation, which led to an increase of repulsion between the dnazyme molecules and a subsequent bending of the microcantilever. this microcantilever sensor could be regenerated, flowing through a strong pb2+ chelator, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. the detection limit of the microcantilever sensor for pb2+ ions is as low as 10(-8) m. the microcantilever sensor also exhibited a high selectivity to pb2+ over other metal ions such as mg2+, fe+, zn2+, ca2+, and cd2+. |
WOS关键词 | GOLD NANOPARTICLES ; LEAD(II) ION ; DNAZYME ; FLUORESCENCE ; SENSOR ; CHEMOSENSORS ; SPECTROMETRY ; ADSORPTION ; PORPHYRINS ; BIOSENSOR |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Analytical |
语种 | 英语 |
WOS记录号 | WOS:000386423300006 |
出版者 | JAPAN SOC ANALYTICAL CHEMISTRY |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2374969 |
专题 | 中国科学院大学 |
通讯作者 | Chen, Bin; Ji, Hai-Feng; Wu, Li-Zhu |
作者单位 | 1.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100190, Peoples R China 3.Nanchang Univ, Coll Chem, Nanchang 330031, Jiangxi, Peoples R China 4.Drexel Univ, Dept Chem, Philadelphia, PA 19010 USA |
推荐引用方式 GB/T 7714 | Peng, Rong-Peng,Xing, Ling-Bao,Wang, Xiao-Jun,et al. Detection of pb2+ in aqueous solution by using a dna-modified microcantilever[J]. Analytical sciences,2016,32(10):1065-1069. |
APA | Peng, Rong-Peng.,Xing, Ling-Bao.,Wang, Xiao-Jun.,Wu, Cheng-juan.,Chen, Bin.,...&Tung, Chen-Ho.(2016).Detection of pb2+ in aqueous solution by using a dna-modified microcantilever.Analytical sciences,32(10),1065-1069. |
MLA | Peng, Rong-Peng,et al."Detection of pb2+ in aqueous solution by using a dna-modified microcantilever".Analytical sciences 32.10(2016):1065-1069. |
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来源:中国科学院大学
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