Immunomodulation of artemisinin and its derivatives
文献类型：期刊论文
| 作者 | Yao, Wenbo1,2; Wang, Feng3; Wang, Hui1,2,3,4 |
| 刊名 | Science bulletin
 |
| 出版日期 | 2016-09-01 |
| 卷号 | 61期号:18页码:1399-1406 |
| 关键词 | Artemisinin Immune system Immune-related diseases Macrophage T-cell B-cell |
| ISSN号 | 2095-9273 |
| DOI | 10.1007/s11434-016-1105-z |
| 通讯作者 | Wang, hui(huiwang@sibs.ac.cn) |
| 英文摘要 | In the 1970s, artemisinin ("qinghaosu" in chinese), a sesquiterpene lactone with an unusual peroxide bridge, was isolated from artemisia annua l. it showed promising antimalarial activity, particularly by eliminating parasites resistant to chloroquine. for more than 30 years, artemisinin has contributed to worldwide health as a new type of antimalarial drug. artemisinin and its analogs, such as dihydroartemisinin, artemether, artesunate, artemiside, artemisone, and arteether, possess not only potent antimalarial activity but also anti-viral, antifungal, anticancer, and anti-inflammatory properties. in this review, we discuss the current understanding of how artemisinin and its analogs affect the immune system and immune-related diseases. |
| WOS关键词 | NF-KAPPA-B ; EXPERIMENTAL RHEUMATOID-ARTHRITIS ; PLASMODIUM-FALCIPARUM MALARIA ; ANTIMALARIAL AGENT ARTESUNATE ; ESCHERICHIA-COLI CHALLENGE ; COLLAGEN-INDUCED ARTHRITIS ; MESSENGER-RNA EXPRESSIONS ; SUB-SAHARAN AFRICA ; T-CELL-ACTIVATION ; SEPSIS MODEL MICE |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000384566600002 |
| 出版者 | SCIENCE PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375042 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, Hui |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Key Lab Food Safety Res, Shanghai 200031, Peoples R China 2.Univ Chinese Acad Sci, Shanghai 200031, Peoples R China 3.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 200031, Peoples R China 4.Minist Hlth, Key Lab Food Safety Risk Assessment, Beijing 100022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yao, Wenbo,Wang, Feng,Wang, Hui. Immunomodulation of artemisinin and its derivatives[J]. Science bulletin,2016,61(18):1399-1406. |
| APA | Yao, Wenbo,Wang, Feng,&Wang, Hui.(2016).Immunomodulation of artemisinin and its derivatives.Science bulletin,61(18),1399-1406. |
| MLA | Yao, Wenbo,et al."Immunomodulation of artemisinin and its derivatives".Science bulletin 61.18(2016):1399-1406. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。