Isolation, stereochemical study, and antioxidant activity of benzofuranone derivatives from a mangrove-derived fungus eurotium rubrum ma-150
文献类型：期刊论文
| 作者 | Meng, Ling-Hong1,2; Mandi, Attila3; Li, Xiao-Ming1; Liu, Yang1,2; Kurtan, Tibor3; Wang, Bin-Gui1 |
| 刊名 | Chirality
 |
| 出版日期 | 2016-08-01 |
| 卷号 | 28期号:8页码:581-584 |
| 关键词 | Marine-derived fungus Benzofuran-1(3h)-one Hplc-ecd Tddft calculations Dpph Radical scavenging activity |
| ISSN号 | 0899-0042 |
| DOI | 10.1002/chir.22613 |
| 通讯作者 | Kurtan, tibor(kurtan.tibor@science.unideb.hu) ; Wang, bin-gui(wangbg@ms.qdio.ac.cn) |
| 英文摘要 | Enantiomers of a 2-benzofuran-1(3h)-one derivative [(-)-1 and (+)-1] and four known analogs (2, 3, 4, 5) were isolated and identified from the culture extract of eurotium rubrum ma-150, a fungus obtained from the mangrove-derived rizospheric soil. their structures were established by detailed interpretation of nuclear magnetic resonance (nmr) data and the structure of (+/-)-1 was confirmed by single-crystal x-ray diffraction analysis. the absolute configuration of the enantiomers (-)-1 and (+)-1 was determined by means of online high-performance liquid chromatography - electronic circular dichroism (hplc-ecd) measurements and time-dependent density functional theory - electronic circular dichroism (tddft-ecd) calculations. compounds (+/-)-1 as well as 2 and 3 exhibited potent dpph radical scavenging activities with ic50 values of 1.23, 2.26, and 3.99 g/ml, respectively. chirality 28:581-584, 2016. (c) 2016 wiley periodicals, inc. |
| WOS关键词 | PESTALOTIOPSIS-MICROSPORA ; ANTHRAQUINONE DERIVATIVES ; PENICILLIUM-BROCAE ; MARINE ; ISOBENZOFURAN ; ANTIFUNGAL |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| WOS类目 | Chemistry, Medicinal ; Chemistry, Analytical ; Chemistry, Organic ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000380950600001 |
| 出版者 | WILEY-BLACKWELL |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375120 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Kurtan, Tibor; Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol,Inst Oceanol, Naihai Rd 7, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Univ Debrecen, Dept Organ Chem, POB 400, H-4002 Debrecen, Hungary |
| 推荐引用方式 GB/T 7714 | Meng, Ling-Hong,Mandi, Attila,Li, Xiao-Ming,et al. Isolation, stereochemical study, and antioxidant activity of benzofuranone derivatives from a mangrove-derived fungus eurotium rubrum ma-150[J]. Chirality,2016,28(8):581-584. |
| APA | Meng, Ling-Hong,Mandi, Attila,Li, Xiao-Ming,Liu, Yang,Kurtan, Tibor,&Wang, Bin-Gui.(2016).Isolation, stereochemical study, and antioxidant activity of benzofuranone derivatives from a mangrove-derived fungus eurotium rubrum ma-150.Chirality,28(8),581-584. |
| MLA | Meng, Ling-Hong,et al."Isolation, stereochemical study, and antioxidant activity of benzofuranone derivatives from a mangrove-derived fungus eurotium rubrum ma-150".Chirality 28.8(2016):581-584. |
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