Highly stable microwave susceptible agents via encapsulation of ti-mineral superfine powders in urea-formaldehyde resin microcapsules for tumor hyperthermia therapy
文献类型：期刊论文
| 作者 | Long, Dan1,2; Mao, Jingsong3; Liu, Tianlong1; Fu, Changhui1; Tan, Longfei1; Ren, Xiangling1; Shi, Haitang1; Su, Hongying3; Ren, Jun1; Meng, Xianwei1 |
| 刊名 | Nanoscale
 |
| 出版日期 | 2016 |
| 卷号 | 8期号:21页码:11044-11051 |
| ISSN号 | 2040-3364 |
| DOI | 10.1039/c6nr01597b |
| 通讯作者 | Meng, xianwei(mengxw@mail.ipc.ac.cn) |
| 英文摘要 | In this study, ti-mineral superfine powders (ti-msp) encapsulated in urea-formaldehyde resin microcapsules (ti-msp@uf-mc) were successfully prepared via a one-step microemulsion method for the first time. because of the strong confinement effects, the ti-msp@uf-mc possessed perfect microwave heating effects. the temperature was 9.3 degrees c higher than that of the saline solution, superior to uf-mc (no significant microwave heating effect, 0 degrees c) and ti-msp (5.1 degrees c). the ti-msp@uf-mc showed low toxicity and good biocompatibility via a series of studies, including a hemolysis study and the mtt assay in vitro and in vivo. when the concentration was below 1000 mu g ml(-1), the hemolysis rate was lower than 5% (hemolysis study). when the concentration was below 400 mu g ml(-1), the cell activity was higher than 80% (mtt assay). moreover, the ti-msp@uf-mc exhibited an ideal ct imaging effect in vivo owing to the large molecular weight of ti-msp. the ti-msp@uf-mc showed a favorable microwave therapy effect in vivo. using mice bearing h22 tumor cells as an animal model, the tumor suppression rate could reach 100%. |
| WOS关键词 | PHOTOTHERMAL THERAPY ; IN-VIVO ; ELECTROPHORETIC PARTICLES ; GOLD NANOPARTICLES ; SILICA NANORATTLES ; CANCER-THERAPY ; DRUG-DELIVERY ; CONVERSION ; CHEMO ; CT |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000380888200022 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375158 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Meng, Xianwei |
| 作者单位 | 1.Chinese Acad Sci, Tech Inst Phys & Chem,Ctr Micro Nanoma & Technol, Key Lab Photochem Convers & Optoelect Mat, Lab Controllable Preparat & Applicat Nanomat, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.China Med Univ, Hosp 1, Dept Radiol, 155 Nanjing North Rd, Shenyang 110001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Long, Dan,Mao, Jingsong,Liu, Tianlong,et al. Highly stable microwave susceptible agents via encapsulation of ti-mineral superfine powders in urea-formaldehyde resin microcapsules for tumor hyperthermia therapy[J]. Nanoscale,2016,8(21):11044-11051. |
| APA | Long, Dan.,Mao, Jingsong.,Liu, Tianlong.,Fu, Changhui.,Tan, Longfei.,...&Meng, Xianwei.(2016).Highly stable microwave susceptible agents via encapsulation of ti-mineral superfine powders in urea-formaldehyde resin microcapsules for tumor hyperthermia therapy.Nanoscale,8(21),11044-11051. |
| MLA | Long, Dan,et al."Highly stable microwave susceptible agents via encapsulation of ti-mineral superfine powders in urea-formaldehyde resin microcapsules for tumor hyperthermia therapy".Nanoscale 8.21(2016):11044-11051. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。