New genotype of avian influenza h5n1 viruses isolated from tree sparrows in china
文献类型：期刊论文
| 作者 | Kou, Z; Lei, FM; Yu, J; Fan, ZJ; Yin, ZH; Jia, CX; Xiong, KJ; Sun, YH; Zhang, XW; Wu, XM |
| 刊名 | Journal of virology
 |
| 出版日期 | 2005-12-01 |
| 卷号 | 79期号:24页码:15460-15466 |
| ISSN号 | 0022-538X |
| DOI | 10.1128/jvi.79.24.15460-15466.2005 |
| 通讯作者 | Lei, fm(litx@wh.iov.cn) |
| 英文摘要 | The 2004 outbreaks of highly pathogenic avian influenza h5n1 disease in china led to a great poultry loss and society attention. a survey of avian influenza viruses was conducted on tree sparrows (passer montanus) collected in china in 2004. four viruses were isolated from free-living tree sparrows. the results of the whole-genome analysis indicated that an h5n1 virus with a new genotype is circulating among tree sparrows. the hemagglutinin and neuraminidase genes of the new genotype were derived from gs/gd/96-like viruses and the nuclear protein gene descended from the 2001 genotype a h5n1 viruses, while the other inner genes originated from an unknown influenza virus. in experimental infection, all four viruses were highly pathogenic to chickens but not pathogenic to ducks or mice. the four tree sparrow viruses were different from the 2003 tree sparrow strain (genotype z) in hong kong. the results suggested that h5n1 viruses might be distributed widely in tree sparrows. |
| WOS关键词 | A VIRUSES ; HONG-KONG ; EVOLUTION ; SWINE ; VIRULENCE ; GENES ; JAPAN |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000234276700047 |
| 出版者 | AMER SOC MICROBIOLOGY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375258 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Lei, FM |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China 2.Chinese Acad Sci, Inst Zool, Beijing 100080, Peoples R China 3.Chinese Acad Sci, Beijing Genom Inst, Beijing 101300, Peoples R China 4.Shaanxi Inst Zool, Xian 710032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Kou, Z,Lei, FM,Yu, J,et al. New genotype of avian influenza h5n1 viruses isolated from tree sparrows in china[J]. Journal of virology,2005,79(24):15460-15466. |
| APA | Kou, Z.,Lei, FM.,Yu, J.,Fan, ZJ.,Yin, ZH.,...&Li, TX.(2005).New genotype of avian influenza h5n1 viruses isolated from tree sparrows in china.Journal of virology,79(24),15460-15466. |
| MLA | Kou, Z,et al."New genotype of avian influenza h5n1 viruses isolated from tree sparrows in china".Journal of virology 79.24(2005):15460-15466. |
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来源：武汉病毒研究所
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