Full-length genome sequences of two sars-like coronaviruses in horseshoe bats and genetic variation analysis
文献类型：期刊论文
| 作者 | Ren, Wuze; Li, Wendong; Yu, Meng; Hao, Pei; Zhang, Yuan; Zhou, Peng; Zhang, Shuyi; Zhao, Guoping; Zhong, Yang; Wang, Shengyue |
| 刊名 | Journal of general virology
 |
| 出版日期 | 2006-11-01 |
| 卷号 | 87页码:3355-3359 |
| ISSN号 | 0022-1317 |
| DOI | 10.1099/vir.0.82220-0 |
| 通讯作者 | Shi, zhengli(zlshi@wh.iov.cn) |
| 英文摘要 | Bats were recently identified as natural reservoirs of sars-like coronavirus (sl-cov) or sars coronavirus-like virus. these viruses, together with sars coronaviruses (sars-cov) isolated from human and palm civet, form a distinctive cluster within the group 2 coronaviruses of the genus coronavirus, tentatively named group 2b (g2b). in this study, complete genome sequences of two additional group 2b coronaviruses (g2b-covs) were determined from horseshoe bat rhinolophus ferrumequinum (g2b-cov rf1) and rhinolophus macrotis (g2b-cov rm1). the bat g2b-cov isolates have an identical genome organization and share an overall genome sequence identity of 88-92% among themselves and between them and the human/civet isolates. the most variable regions are located in the genes encoding nsp3, orf3a, spike protein and orf8 when bat and human/civet g2b-cov isolates are compared. genetic analysis demonstrated that a diverse g2b-cov population exists in the bat habitat and has evolved from a common ancestor of sars-cov. |
| WOS关键词 | ACUTE RESPIRATORY SYNDROME ; MOLECULAR EVOLUTION ; VIRUS ; CHINA ; ALIGNMENT ; RECEPTOR ; CIVETS ; SITE |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Virology |
| WOS类目 | Biotechnology & Applied Microbiology ; Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000241542100026 |
| 出版者 | SOC GENERAL MICROBIOLOGY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375286 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Shi, Zhengli |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Virol, Inst Virol, Wuhan 430071, Hubei, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Inst Zool, Beijing 100080, Peoples R China 4.CSIRO, Australian Anim Hlth Lab, Geelong, Vic 3220, Australia 5.Shanghai Ctr Bioinformat Technol, Shanghai 200235, Peoples R China 6.Fudan Univ, Sch Life Sci, Shanghai 200433, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ren, Wuze,Li, Wendong,Yu, Meng,et al. Full-length genome sequences of two sars-like coronaviruses in horseshoe bats and genetic variation analysis[J]. Journal of general virology,2006,87:3355-3359. |
| APA | Ren, Wuze.,Li, Wendong.,Yu, Meng.,Hao, Pei.,Zhang, Yuan.,...&Shi, Zhengli.(2006).Full-length genome sequences of two sars-like coronaviruses in horseshoe bats and genetic variation analysis.Journal of general virology,87,3355-3359. |
| MLA | Ren, Wuze,et al."Full-length genome sequences of two sars-like coronaviruses in horseshoe bats and genetic variation analysis".Journal of general virology 87(2006):3355-3359. |
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来源：武汉病毒研究所
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