Biochips for detection of dna mutations
文献类型:期刊论文
作者 | Bi, LJ; Zhang, XE; Zhou, YF; Deng, JY |
刊名 | Current analytical chemistry
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出版日期 | 2006-07-01 |
卷号 | 2期号:3页码:323-330 |
关键词 | Dna mutations Genetic diseases Drug resistance Biochip Detection |
ISSN号 | 1573-4110 |
通讯作者 | Zhang, xe() |
英文摘要 | Dna mutation is the major cause of gene evolution. the variation of dna sequence may result in genetic diseases. genotypes. single nucleotide polymorphism, and drug resistance of pathogens. using biochip technologies, detection of mutations can be performed in parallel under identical conditions, hereby providing a solution to continuously increasing demands for large-scale genetic analysis. this article reviews the development of the biochips for mutation analysis. features, limitations and applications of various principles are discussed. |
WOS关键词 | RESISTANT MYCOBACTERIUM-TUBERCULOSIS ; OLIGONUCLEOTIDE LIGATION ASSAY ; GRADIENT GEL-ELECTROPHORESIS ; BASE-PAIR MISMATCHES ; LARGE-SCALE ; GENE-EXPRESSION ; GENOMIC DNA ; PCR ; MICROARRAYS ; DIAGNOSTICS |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Analytical |
语种 | 英语 |
WOS记录号 | WOS:000238677800009 |
出版者 | BENTHAM SCIENCE PUBL LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375325 |
专题 | 武汉病毒研究所 |
通讯作者 | Zhang, XE |
作者单位 | 1.Chinese Acad Sci, State Key Lab Biomacromol, Joint Res Grp Analyt Pathogenic Microbiol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Biophys, State Key Lab Virol, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Wuhan Inst Virol, Beijing 100101, Peoples R China |
推荐引用方式 GB/T 7714 | Bi, LJ,Zhang, XE,Zhou, YF,et al. Biochips for detection of dna mutations[J]. Current analytical chemistry,2006,2(3):323-330. |
APA | Bi, LJ,Zhang, XE,Zhou, YF,&Deng, JY.(2006).Biochips for detection of dna mutations.Current analytical chemistry,2(3),323-330. |
MLA | Bi, LJ,et al."Biochips for detection of dna mutations".Current analytical chemistry 2.3(2006):323-330. |
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来源:武汉病毒研究所
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