Sensitive and selective electrochemical detection of artemisinin based on its reaction with p-aminophenylboronic acid
文献类型：期刊论文
| 作者 | Wang, Chao1,2; Zholudov, Yuriy T.2,3; Nsabimana, Anaclet2,4; Xu, Guobao1,2; Li, Jianping1 |
| 刊名 | Analytica chimica acta
 |
| 出版日期 | 2016-09-21 |
| 卷号 | 937页码:39-42 |
| 关键词 | Artemisinin P-aminophenylboronic acid P-aminophenol Electrochemical sensor |
| ISSN号 | 0003-2670 |
| DOI | 10.1016/j.aca.2016.07.026 |
| 通讯作者 | Xu, guobao(guobaoxu@ciac.ac.cn) ; Li, jianping(likianping@glut.edu.cn) |
| 英文摘要 | The electrochemical detection of artemisinin generally requires high oxidation potential or the use of complex electrode modification. we find that artemisinin can react with p-aminophenylboronic acid to produce easily electrochemically detectable aminophenol for the first time. by making use of the new reaction, we report an alternative method to detect artemisinin through the determination of p-aminophenol. the calibration curve for the determination of artemisinin is linear in the range of 2 mu mol l-1 to 200 mu mol l-1 with the detection limit of 0.8 mu mol l-1, which is more sensitive than other reported electrochemical methods. the relative standard deviation is 4.83% for the determination of 10 mu m artemisinin. because the oxidation potential of p-aminophenol is around 0 v, the present method is high selective. when 40 mu m, 90 mu m and 140 mu m of artemisinin were spiked to compound naphthoquine phosphate tablet samples, the recoveries are 107.6%, 105.4% and 101.7%, respectively. this detection strategy is attractive for the detection of artemisinin and its derivatives. the finding that artemisinin can react with aromatic boronic acid has the potential to be exploited for the development of other sensors, such as fluorescence artemisinin sensors. (c) 2016 elsevier b.v. all rights reserved. |
| WOS关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY ; MODIFIED ELECTRODE ; HYDROGEN-PEROXIDE ; DIHYDROARTEMISININ ; ENDOPEROXIDE ; EXTRACTION ; ARTESUNATE ; MALARIA ; PLASMA ; SERUM |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000382252800005 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375331 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Xu, Guobao; Li, Jianping |
| 作者单位 | 1.Guilin Univ Technol, Coll Chem & Bioengn, Guilin 541004, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China 3.Kharkiv Natl Univ Radio Elect, Lab Analyt Optochemotron, 14 Nauka Ave, UA-61166 Kharkov, Ukraine 4.Chinese Acad Sci, Univ Chinese Acad Sci, 19A Yuquanlu, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Chao,Zholudov, Yuriy T.,Nsabimana, Anaclet,et al. Sensitive and selective electrochemical detection of artemisinin based on its reaction with p-aminophenylboronic acid[J]. Analytica chimica acta,2016,937:39-42. |
| APA | Wang, Chao,Zholudov, Yuriy T.,Nsabimana, Anaclet,Xu, Guobao,&Li, Jianping.(2016).Sensitive and selective electrochemical detection of artemisinin based on its reaction with p-aminophenylboronic acid.Analytica chimica acta,937,39-42. |
| MLA | Wang, Chao,et al."Sensitive and selective electrochemical detection of artemisinin based on its reaction with p-aminophenylboronic acid".Analytica chimica acta 937(2016):39-42. |
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来源：中国科学院大学
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