Molecular patterns of avian influenza a viruses
文献类型:期刊论文
作者 | Kou Zheng1,2; Lei FuMin3; Wang ShengYue4; Zhou YanHong1; Li TianXian2 |
刊名 | Chinese science bulletin
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出版日期 | 2008-07-01 |
卷号 | 53期号:13页码:2002-2007 |
关键词 | Avian influenza a virus H5n1 Wavelet packet decomposition Clustering Interspecies transmission |
ISSN号 | 1001-6538 |
DOI | 10.1007/s11434-008-0236-2 |
通讯作者 | Zhou yanhong(yhzhou@mail.hust.edu.cn) |
英文摘要 | Avian influenza a viruses could get across the species barrier and be fatal to humans. highly pathogenic avian influenza h5n1 virus was an example. the mechanism of interspecies transmission is not clear as yet. in this research, the protein sequences of 237 influenza a viruses with different subtypes were transformed into pseudo-signals. the energy features were extracted by the method of wavelet packet decomposition and used for virus classification by the method of hierarchical clustering. the clustering results showed that five patterns existed in avian influenza a viruses, which associated with the phenotype of interspecies transmission, and that avian viruses with patterns c and e could across species barrier and those with patterns a, b and d might not have the abilities. the results could be used to construct an early warning system to predict the transmissibility of avian influenza a viruses to humans. |
WOS关键词 | H5N1 VIRUS ; HONG-KONG ; INFECTION ; CHINA ; EVOLUTION ; H9N2 ; ASIA |
WOS研究方向 | Science & Technology - Other Topics |
WOS类目 | Multidisciplinary Sciences |
语种 | 英语 |
WOS记录号 | WOS:000257327400013 |
出版者 | SCIENCE PRESS |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375422 |
专题 | 武汉病毒研究所 |
通讯作者 | Zhou YanHong |
作者单位 | 1.Huazhong Univ Sci & Technol, Hubei Bioinformat & Mol Imaging Key Lab, Dept Syst Biol, Wuhan 430074, Peoples R China 2.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China 3.Chinese Acad Sci, Inst Zool, Beijing 100080, Peoples R China 4.Chinese Acad Sci, Chinese Natl Human Genome Ctr, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Kou Zheng,Lei FuMin,Wang ShengYue,et al. Molecular patterns of avian influenza a viruses[J]. Chinese science bulletin,2008,53(13):2002-2007. |
APA | Kou Zheng,Lei FuMin,Wang ShengYue,Zhou YanHong,&Li TianXian.(2008).Molecular patterns of avian influenza a viruses.Chinese science bulletin,53(13),2002-2007. |
MLA | Kou Zheng,et al."Molecular patterns of avian influenza a viruses".Chinese science bulletin 53.13(2008):2002-2007. |
入库方式: iSwitch采集
来源:武汉病毒研究所
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