中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Molecular patterns of avian influenza a viruses

文献类型:期刊论文

作者Kou Zheng1,2; Lei FuMin3; Wang ShengYue4; Zhou YanHong1; Li TianXian2
刊名Chinese science bulletin
出版日期2008-07-01
卷号53期号:13页码:2002-2007
关键词Avian influenza a virus H5n1 Wavelet packet decomposition Clustering Interspecies transmission
ISSN号1001-6538
DOI10.1007/s11434-008-0236-2
通讯作者Zhou yanhong(yhzhou@mail.hust.edu.cn)
英文摘要Avian influenza a viruses could get across the species barrier and be fatal to humans. highly pathogenic avian influenza h5n1 virus was an example. the mechanism of interspecies transmission is not clear as yet. in this research, the protein sequences of 237 influenza a viruses with different subtypes were transformed into pseudo-signals. the energy features were extracted by the method of wavelet packet decomposition and used for virus classification by the method of hierarchical clustering. the clustering results showed that five patterns existed in avian influenza a viruses, which associated with the phenotype of interspecies transmission, and that avian viruses with patterns c and e could across species barrier and those with patterns a, b and d might not have the abilities. the results could be used to construct an early warning system to predict the transmissibility of avian influenza a viruses to humans.
WOS关键词H5N1 VIRUS ; HONG-KONG ; INFECTION ; CHINA ; EVOLUTION ; H9N2 ; ASIA
WOS研究方向Science & Technology - Other Topics
WOS类目Multidisciplinary Sciences
语种英语
WOS记录号WOS:000257327400013
出版者SCIENCE PRESS
URI标识http://www.irgrid.ac.cn/handle/1471x/2375422
专题武汉病毒研究所
通讯作者Zhou YanHong
作者单位1.Huazhong Univ Sci & Technol, Hubei Bioinformat & Mol Imaging Key Lab, Dept Syst Biol, Wuhan 430074, Peoples R China
2.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China
3.Chinese Acad Sci, Inst Zool, Beijing 100080, Peoples R China
4.Chinese Acad Sci, Chinese Natl Human Genome Ctr, Shanghai 201203, Peoples R China
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Kou Zheng,Lei FuMin,Wang ShengYue,et al. Molecular patterns of avian influenza a viruses[J]. Chinese science bulletin,2008,53(13):2002-2007.
APA Kou Zheng,Lei FuMin,Wang ShengYue,Zhou YanHong,&Li TianXian.(2008).Molecular patterns of avian influenza a viruses.Chinese science bulletin,53(13),2002-2007.
MLA Kou Zheng,et al."Molecular patterns of avian influenza a viruses".Chinese science bulletin 53.13(2008):2002-2007.

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来源:武汉病毒研究所

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