Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum
文献类型:期刊论文
作者 | Zhang, Yonggang1,2,3; Tian, Renrong4; Liu, Shuchun1,3; Chen, Xulin4; Liu, Xingzhong1,3; Che, Yongsheng1,3 |
刊名 | Bioorganic & medicinal chemistry
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出版日期 | 2008-03-01 |
卷号 | 16期号:5页码:2627-2634 |
关键词 | Stachybotrys charatum Alachalasins Anti-hiv Antibacterial |
ISSN号 | 0968-0896 |
DOI | 10.1016/j.bmc.2007.11.042 |
通讯作者 | Che, yongsheng(cheys@im.ac.cn) |
英文摘要 | Alachalasins a-g (1-7), seven new cytochalasin-type of metabolites, have been isolated from cultures of an isolate of stachybotrys charatum. the structures of these compounds were determined mainly by analysis of their nmr spectroscopic data, and the absolute configuration of 1 was assigned by application of the modified mosher method. alachalasin a (1) displayed inhibitory effect on hiv-1(lai) replication in c8166 cells with an ec50 of 8-01 mu m; alachalasins d (4) and g (7) showed modest antimicrobial activity. (c) 2007 elsevier ltd. all rights reserved. |
WOS关键词 | LIPID DROPLET FORMATION ; NUCLEAR MAGNETIC-RESONANCE ; MOUSE MACROPHAGES ; HIV-1 PROTEASE ; PHOMOPSIS SP ; BIOSYNTHESIS ; METABOLITES ; INHIBITOR ; PHENOCHALASINS ; CHAETOMIUM |
WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
WOS类目 | Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Chemistry, Organic |
语种 | 英语 |
WOS记录号 | WOS:000255002400041 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375501 |
专题 | 武汉病毒研究所 |
通讯作者 | Che, Yongsheng |
作者单位 | 1.Chinese Acad Sci, Inst Microbiol, Key Lab Systemat Mycol & Lichenol, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Inst Microbiol, Ctr Bioenergy & Ind Biotechnol, Beijing 100080, Peoples R China 4.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Yonggang,Tian, Renrong,Liu, Shuchun,et al. Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum[J]. Bioorganic & medicinal chemistry,2008,16(5):2627-2634. |
APA | Zhang, Yonggang,Tian, Renrong,Liu, Shuchun,Chen, Xulin,Liu, Xingzhong,&Che, Yongsheng.(2008).Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum.Bioorganic & medicinal chemistry,16(5),2627-2634. |
MLA | Zhang, Yonggang,et al."Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum".Bioorganic & medicinal chemistry 16.5(2008):2627-2634. |
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来源:武汉病毒研究所
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