中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum

文献类型:期刊论文

作者Zhang, Yonggang1,2,3; Tian, Renrong4; Liu, Shuchun1,3; Chen, Xulin4; Liu, Xingzhong1,3; Che, Yongsheng1,3
刊名Bioorganic & medicinal chemistry
出版日期2008-03-01
卷号16期号:5页码:2627-2634
关键词Stachybotrys charatum Alachalasins Anti-hiv Antibacterial
ISSN号0968-0896
DOI10.1016/j.bmc.2007.11.042
通讯作者Che, yongsheng(cheys@im.ac.cn)
英文摘要Alachalasins a-g (1-7), seven new cytochalasin-type of metabolites, have been isolated from cultures of an isolate of stachybotrys charatum. the structures of these compounds were determined mainly by analysis of their nmr spectroscopic data, and the absolute configuration of 1 was assigned by application of the modified mosher method. alachalasin a (1) displayed inhibitory effect on hiv-1(lai) replication in c8166 cells with an ec50 of 8-01 mu m; alachalasins d (4) and g (7) showed modest antimicrobial activity. (c) 2007 elsevier ltd. all rights reserved.
WOS关键词LIPID DROPLET FORMATION ; NUCLEAR MAGNETIC-RESONANCE ; MOUSE MACROPHAGES ; HIV-1 PROTEASE ; PHOMOPSIS SP ; BIOSYNTHESIS ; METABOLITES ; INHIBITOR ; PHENOCHALASINS ; CHAETOMIUM
WOS研究方向Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Chemistry, Organic
语种英语
WOS记录号WOS:000255002400041
出版者PERGAMON-ELSEVIER SCIENCE LTD
URI标识http://www.irgrid.ac.cn/handle/1471x/2375501
专题武汉病毒研究所
通讯作者Che, Yongsheng
作者单位1.Chinese Acad Sci, Inst Microbiol, Key Lab Systemat Mycol & Lichenol, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Chinese Acad Sci, Inst Microbiol, Ctr Bioenergy & Ind Biotechnol, Beijing 100080, Peoples R China
4.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Yonggang,Tian, Renrong,Liu, Shuchun,et al. Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum[J]. Bioorganic & medicinal chemistry,2008,16(5):2627-2634.
APA Zhang, Yonggang,Tian, Renrong,Liu, Shuchun,Chen, Xulin,Liu, Xingzhong,&Che, Yongsheng.(2008).Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum.Bioorganic & medicinal chemistry,16(5),2627-2634.
MLA Zhang, Yonggang,et al."Alachalasins a-g, new cytochalasins from the fungus stachybotrys charatum".Bioorganic & medicinal chemistry 16.5(2008):2627-2634.

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来源:武汉病毒研究所

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