First detection of a novel hiv type 1 crf01_ae/07_bc recombinant among an epidemiologically linked cohort of idus in jiangsu, china
文献类型：期刊论文
| 作者 | Guo, Hongxiong1,2; Guo, Dongmei1; Wei, Ji-Fu3; Yang, Haitao2; Huan, Xiping2; Tsui, Stephen Kwok-Wing4,5; Yang, Rongge6; Zhang, Chiyu1 |
| 刊名 | Aids research and human retroviruses
 |
| 出版日期 | 2009-04-01 |
| 卷号 | 25期号:4页码:463-467 |
| ISSN号 | 0889-2229 |
| DOI | 10.1089/aid.2008.0250 |
| 通讯作者 | Zhang, chiyu(zhangcy1999@hotmail.com) |
| 英文摘要 | Our recent study showed that almost equal proportions of b, crfs_bc, and crf01_ae were circulating among msm in jiangsu, suggesting that there is a very high likelihood of generating new intersubtypes/crfs recombinants. here, we report an epidemiologically linked cohort including 22 hiv-1-positive idus in jiangsu. fifteen blood samples were collected to investigate hiv-1 subtype characterization. the analyses of gag-rt regions showed that 14 of these samples belonged to crf07_bc. importantly, we detected, for the first time, a novel second-generation hiv-1 recombinant (07jsnj001) between crf01_ae and crf07_bc. the analyses of the near full-length genomic sequence of 07jsnj001 (genbank accession number fj238521) showed that 07jsnj001 is composed of at least 10 interlaced crf07_bc and crf01_ae segments, quite distinct from any previously identified crf and urf around the world. the detection of the crf01_ae/crf07_bc recombinant may be a harbinger of more new intersubtypes/crfs recombinants occurring in jiangsu province. |
| WOS关键词 | LENGTH SEQUENCE-ANALYSIS ; KUALA-LUMPUR ; IDENTIFICATION ; THAILAND ; MALAYSIA ; FORMS ; CRF15-01B ; PROVINCE |
| WOS研究方向 | Immunology ; Infectious Diseases ; Virology |
| WOS类目 | Immunology ; Infectious Diseases ; Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000265087900012 |
| 出版者 | MARY ANN LIEBERT INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375562 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Zhang, Chiyu |
| 作者单位 | 1.Jiangsu Univ, Inst Life Sci, Zhenjiang 212013, Jiangsu, Peoples R China 2.Jiangsu Ctr Dis Control & Prevent, Nanjing 210009, Jiangsu, Peoples R China 3.Nanjing Med Univ, Affiliated Hosp 1, Clin Expt Ctr, Nanjing 210029, Jiangsu, Peoples R China 4.Hong Kong Bioinformat Ctr, Hong Kong, Hong Kong, Peoples R China 5.Chinese Univ Hong Kong, Dept Biochem, Hong Kong, Hong Kong, Peoples R China 6.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, HIV Mol Epidemiol & Virol Res Grp, Wuhan 430071, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Hongxiong,Guo, Dongmei,Wei, Ji-Fu,et al. First detection of a novel hiv type 1 crf01_ae/07_bc recombinant among an epidemiologically linked cohort of idus in jiangsu, china[J]. Aids research and human retroviruses,2009,25(4):463-467. |
| APA | Guo, Hongxiong.,Guo, Dongmei.,Wei, Ji-Fu.,Yang, Haitao.,Huan, Xiping.,...&Zhang, Chiyu.(2009).First detection of a novel hiv type 1 crf01_ae/07_bc recombinant among an epidemiologically linked cohort of idus in jiangsu, china.Aids research and human retroviruses,25(4),463-467. |
| MLA | Guo, Hongxiong,et al."First detection of a novel hiv type 1 crf01_ae/07_bc recombinant among an epidemiologically linked cohort of idus in jiangsu, china".Aids research and human retroviruses 25.4(2009):463-467. |
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来源：武汉病毒研究所
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