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Preparation and anti-tmv activity of guanidinylated chitosan hydrochloride

文献类型:期刊论文

作者Hu, Ying1; Cai, Jun1; Du, Yumin2; Lin, Jianguo1; Wang, Changgao1; Xiong, Kejuan3
刊名Journal of applied polymer science
出版日期2009-06-15
卷号112期号:6页码:3522-3528
关键词Guanidinylated chitosan hydrochloride Tmv Antiviral activity
ISSN号0021-8995
DOI10.1002/app.29959
通讯作者Hu, ying(yinghu2000@163.com)
英文摘要In this study, guanidinylated chitosan hydrochloride (gch) was synthesized and its structure was characterized by uv-vis and ftir. the degree of substitution of guanidinylated chitosan was confirmed by elemental analysis. in vitro antiviral activity of guanidinium derivative on local infection and systemic infection of tobacco mosaic virus (tmv) inoculated were evaluated by semileaf method using different modes of gch application and antiserum assay. meanwhile, the morphological characteristic of virus treated by gch was performed by transmission electron microscope. the results showed that gch had better antiviral activity than chitosan. the average inhibitory rate of gch on local infection was 84%, which was much higher than that of chitosan hydrochloride. it was shown that the guanidinylated chitosan was an efficient passivator, and its antiviral effect decreased after mechanical inoculation. the guanidinylated chitosan increased the resistance of plant against tmv and decreased the infection of the virus. the electron microscope photograph exhibited that gch not only directly altered the configuration of tmv but also congregated and reduced the virus. (c) 2009 wiley periodicals, inc. j appl polym sci 112: 3522-3528, 2009
WOS关键词DISEASE RESISTANCE RESPONSE ; AMINOGLYCOSIDE ANTIBIOTICS ; DEFENSE RESPONSES ; FUSARIUM-SOLANI ; PEA ; ELICITATION ; DERIVATIVES ; INHIBITORS ; ANALOGS ; SUGARS
WOS研究方向Polymer Science
WOS类目Polymer Science
语种英语
WOS记录号WOS:000265422100045
出版者JOHN WILEY & SONS INC
URI标识http://www.irgrid.ac.cn/handle/1471x/2375627
专题武汉病毒研究所
通讯作者Hu, Ying
作者单位1.Hubei Univ Technol, Coll Bioengn, Hubei Prov Key Lab Ind Microbiol, Key Lab Fermentat Engn Minister Educ, Wuhan 430068, Peoples R China
2.Wuhan Univ, Dept Environm Sci, Coll Resource & Environm Sci, Wuhan 430079, Peoples R China
3.Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430072, Peoples R China
推荐引用方式
GB/T 7714
Hu, Ying,Cai, Jun,Du, Yumin,et al. Preparation and anti-tmv activity of guanidinylated chitosan hydrochloride[J]. Journal of applied polymer science,2009,112(6):3522-3528.
APA Hu, Ying,Cai, Jun,Du, Yumin,Lin, Jianguo,Wang, Changgao,&Xiong, Kejuan.(2009).Preparation and anti-tmv activity of guanidinylated chitosan hydrochloride.Journal of applied polymer science,112(6),3522-3528.
MLA Hu, Ying,et al."Preparation and anti-tmv activity of guanidinylated chitosan hydrochloride".Journal of applied polymer science 112.6(2009):3522-3528.

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来源:武汉病毒研究所

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