Effect of molecular structure on stability of organic nanoparticles formed by bodipy dimers
文献类型：期刊论文
| 作者 | Lin, Wenhai1,2; Zhang, Wei1,2; Sun, Tingting1,2; Gu, Jingkai3; Xie, Zhigang1; Jing, Xiabin1 |
| 刊名 | Langmuir
 |
| 出版日期 | 2016-09-20 |
| 卷号 | 32期号:37页码:9575-9581 |
| ISSN号 | 0743-7463 |
| DOI | 10.1021/acs.langmuir.6b02118 |
| 通讯作者 | Xie, zhigang(xiez@ciac.ac.cn) |
| 英文摘要 | The objective was to evaluate the stability of organic nanoparticles made from. bodipy dimers. bodipy dimers with different length of linkers were synthesized via multicomponent passerini reaction, and could form the fluorescent nanoparticles (fnps) through nanoprecipitation. bodipy-dimers fnps with long chain linker indicated better stability in biological condition than those with short one as revealed by changes. of diameter and size distribution. the fnps possessed high physical homogeneity and low cytotoxicity. the molecular structure dependent stability was also, validated by confocal laser scanning microscope based on the dissociation-induced fluorescence recovering. importantly, stable fnps also could be used to load hydrophobic cargoes and deliver them into cytoplasm. we believe this systematic study between structure and stability might open new opportunities for designing stable nanoparticles for various applications. |
| WOS关键词 | DRUG-DELIVERY ; IN-VIVO ; PASSERINI REACTION ; SPECTROSCOPIC PROPERTIES ; PHOTOTHERMAL THERAPY ; CANCER-THERAPY ; QUANTUM DOTS ; CARBON DOTS ; NANOCARRIERS ; NANOPROBES |
| WOS研究方向 | Chemistry ; Materials Science |
| WOS类目 | Chemistry, Multidisciplinary ; Chemistry, Physical ; Materials Science, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000384038200024 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375779 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Xie, Zhigang |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Jilin Univ, Coll Life Sci, Res Ctr Drug Metab, Changchun 130012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Wenhai,Zhang, Wei,Sun, Tingting,et al. Effect of molecular structure on stability of organic nanoparticles formed by bodipy dimers[J]. Langmuir,2016,32(37):9575-9581. |
| APA | Lin, Wenhai,Zhang, Wei,Sun, Tingting,Gu, Jingkai,Xie, Zhigang,&Jing, Xiabin.(2016).Effect of molecular structure on stability of organic nanoparticles formed by bodipy dimers.Langmuir,32(37),9575-9581. |
| MLA | Lin, Wenhai,et al."Effect of molecular structure on stability of organic nanoparticles formed by bodipy dimers".Langmuir 32.37(2016):9575-9581. |
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来源：中国科学院大学
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