Prediction of interspecies transmission for avian influenza a virus based on a back-propagation neural network
文献类型：期刊论文
| 作者 | Qiang, Xiaoli2,3,4; Kou, Zheng1 |
| 刊名 | Mathematical and computer modelling
 |
| 出版日期 | 2010-12-01 |
| 卷号 | 52期号:11-12页码:2060-2065 |
| 关键词 | Avian influenza a virus Bp neural network Interspecies transmission |
| ISSN号 | 0895-7177 |
| DOI | 10.1016/j.mcm.2010.06.008 |
| 通讯作者 | Kou, zheng(kouz2004@sohu.com) |
| 英文摘要 | Avian influenza a viruses could cross the barrier and infect human beings. we need to predict which subtypes and strains of avian influenza virus will become capable of interspecies transmission, which is very important for public health. recently, two categories of molecular patterns, which were associated with the phenotype of interspecies transmission, were found to exist among avian influenza a viruses with different subtypes. in this study, we used a method based on wavelet packet decomposition to transform the viral sequences and used the energy features of the viral genome as input to train a back-propagation (bp) neural network. the average output values for test samples were 0.0125 and 0.0092. the good results of the experimentation were used to discriminate the two categories of molecular patterns. a novel method was constructed to predict the transmissibility of avian influenza a viruses, which is very useful for public health. it was also anticipated that the current classification method would be a useful tool based on the development of large-scale genome sequencing of the influenza a virus. (c) 2010 elsevier ltd. all rights reserved. |
| WOS关键词 | H5N1 VIRUS ; HONG-KONG ; INFECTION ; CHINA ; H9N2 ; ASIA |
| WOS研究方向 | Computer Science ; Mathematics |
| WOS类目 | Computer Science, Interdisciplinary Applications ; Computer Science, Software Engineering ; Mathematics, Applied |
| 语种 | 英语 |
| WOS记录号 | WOS:000281614600018 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375783 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Kou, Zheng |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China 2.Peking Univ, Sch Elect Engn & Comp Sci, Beijing 100871, Peoples R China 3.Peking Univ, Key Lab High Confidence Software Technol, Minist Educ, Beijing 100871, Peoples R China 4.S Cent Univ Nationalities, Coll Comp Sci, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiang, Xiaoli,Kou, Zheng. Prediction of interspecies transmission for avian influenza a virus based on a back-propagation neural network[J]. Mathematical and computer modelling,2010,52(11-12):2060-2065. |
| APA | Qiang, Xiaoli,&Kou, Zheng.(2010).Prediction of interspecies transmission for avian influenza a virus based on a back-propagation neural network.Mathematical and computer modelling,52(11-12),2060-2065. |
| MLA | Qiang, Xiaoli,et al."Prediction of interspecies transmission for avian influenza a virus based on a back-propagation neural network".Mathematical and computer modelling 52.11-12(2010):2060-2065. |
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来源：武汉病毒研究所
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