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Hantavirus outbreak associated with laboratory rats in yunnan, china

文献类型:期刊论文

作者Zhang, Yunzhi1,2; Zhang, Hailin1; Dong, Xingqi1; Yuan, Junfa2; Zhang, Huajun2; Yang, Xinglou2; Zhou, Peng2; Ge, Xingyi2; Li, Yan2; Wang, Lin-Fa3
刊名Infection genetics and evolution
出版日期2010-07-01
卷号10期号:5页码:638-644
关键词Hemorrhagic fever with renal syndrome Hantavirus Laboratory rats Recombination
ISSN号1567-1348
DOI10.1016/j.meegid.2010.03.015
通讯作者Zhang, hailin(zhanghl715@163.com)
英文摘要An outbreak of hemorrhagic fever with renal syndrome occurred among students in a college (college a) in kunming, yunnan province, china in 2003. subsequent investigations revealed the presence of hantavirus antibodies and antigens in laboratory rats at college a and two other institutions. hantavirus antibodies were detected in 15 additional individuals other than the index case in these three locations. epidemiologic data indicated that the human infections were a result of zoonotic transmission of the virus from laboratory rats. a virus was isolated from rats in college a and the full-length genome sequence revealed that this was a new hantaan virus isolate, designated strain ky. sequence analysis of the three genome segments indicated that this new isolate is a reassortant derived from human and rat hantaan viruses. further sequence analysis of the medium (m) genome segment revealed that it originated from a recombination event between two rat hantaan virus lineages. (c) 2010 elsevier b.v. all rights reserved.
WOS关键词KOREAN HEMORRHAGIC-FEVER ; RENAL SYNDROME ; SEQUENCE ALIGNMENT ; HANTAAN VIRUS ; RECOMBINATION ; DIVERSITY ; GUIZHOU ; DISEASE ; HFRS
WOS研究方向Infectious Diseases
WOS类目Infectious Diseases
语种英语
WOS记录号WOS:000279035800007
出版者ELSEVIER SCIENCE BV
URI标识http://www.irgrid.ac.cn/handle/1471x/2375797
专题武汉病毒研究所
通讯作者Zhang, Hailin
作者单位1.Yunnan Inst Endem Dis Control & Prevent, Dali, Peoples R China
2.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan, Peoples R China
3.Commonwealth Sci & Ind Res Org Livestock Ind, Geelong, Vic, Australia
推荐引用方式
GB/T 7714
Zhang, Yunzhi,Zhang, Hailin,Dong, Xingqi,et al. Hantavirus outbreak associated with laboratory rats in yunnan, china[J]. Infection genetics and evolution,2010,10(5):638-644.
APA Zhang, Yunzhi.,Zhang, Hailin.,Dong, Xingqi.,Yuan, Junfa.,Zhang, Huajun.,...&Shi, Zhengli.(2010).Hantavirus outbreak associated with laboratory rats in yunnan, china.Infection genetics and evolution,10(5),638-644.
MLA Zhang, Yunzhi,et al."Hantavirus outbreak associated with laboratory rats in yunnan, china".Infection genetics and evolution 10.5(2010):638-644.

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来源:武汉病毒研究所

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