Structural characterization of iridoid glucosides by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry
文献类型：期刊论文
| 作者 | Li, Cun-man; Zhang, Xiu-li; Xue, Xing-ya; Zhang, Fei-fang; Xu, Qing; Liang, Xin-miao |
| 刊名 | rapid communications in mass spectrometry
 |
| 出版日期 | 2008-06-01 |
| 卷号 | 22期号:12页码:1941-1954 |
| 产权排序 | 1;1 |
| 通讯作者 | 梁鑫淼 |
| 英文摘要 | the mass spectral fragmentation behavior of ten iridoid glucosides (igs) has been studied using electrospray ionization (esi), collision-induced dissociation (cid), and quadrupole time-of-flight tandem mass spectrometry (q-tof ms/ms). in the negative esi mass spectra, the deprotonated [m-h](-) ion was observed for all of the ten igs except gardoside methyl ester, while the formate adduct [m+hcoo](-) ion appeared to be favored by the presence of a methyl ester or a lactone group in the c-4 position when formic acid was added to the mobile phase. the cid ms/ms spectra of the [m-h](-) ions have been used for structural elucidation. ring cleavages of the aglycone moiety have been observed in the ms/ms spectra, corresponding to f-1,4(-), f-2,6(-), f-2,7(-), and f-2,7(0)- ions, based on accurate mass measurements and the elemental compositions of the product ions. these characteristic ions gave valuable information on the basic structural skeletons. furthermore, on the basis of the relative abundances of the fragment ions (1,4)f(-)and f-2,7(-), different sub-classes, such as cyclopentarte-type and 7,8-cyclopentene-type igs, can be differentiated. ring cleavage of the sugar moieties was also observed, yielding useful information for their characterization. in addition, the neutral losses, such as h2o, co2, ch3oh, ch3cooh, and glucosidic units, have proved useful for confirming the presence of functional substituents in the structures of the igs. based on the fragmentation patterns of these standard igs, twelve igs have been characterized in an extract of hedyotis diffusa willd. by means of ultra-performance liquid chromatography/q-tof ms/ms, of which six have been unambiguously identified and the other six have been tentatively identified. copyright (c) 2008 john wiley & sons, ltd. |
| WOS标题词 | science & technology ; physical sciences ; technology |
| 类目[WOS] | chemistry, analytical ; spectroscopy |
| 研究领域[WOS] | chemistry ; spectroscopy |
| 关键词[WOS] | collision-induced dissociation ; electrospray-ionization ; phenylethanoid glycosides ; monoterpene glucosides ; metal cationization ; paederia-scandens ; fragmentation ; constituents ; diffusa |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000256985100021 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/100683]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Cun-man,Zhang, Xiu-li,Xue, Xing-ya,et al. Structural characterization of iridoid glucosides by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry[J]. rapid communications in mass spectrometry,2008,22(12):1941-1954. |
| APA | Li, Cun-man,Zhang, Xiu-li,Xue, Xing-ya,Zhang, Fei-fang,Xu, Qing,&Liang, Xin-miao.(2008).Structural characterization of iridoid glucosides by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.rapid communications in mass spectrometry,22(12),1941-1954. |
| MLA | Li, Cun-man,et al."Structural characterization of iridoid glucosides by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry".rapid communications in mass spectrometry 22.12(2008):1941-1954. |
入库方式： OAI收割
来源：大连化学物理研究所
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