Emergence of genotype i of japanese encephalitis virus as the dominant genotype in asia
文献类型：期刊论文
| 作者 | Pan, Xiao-Ling1; Liu, Hong1; Wang, Huan-Yu1; Fu, Shi-Hong1; Liu, Hai-Zhou2; Zhang, Hai-Lin3; Li, Ming-Hua1; Gao, Xiao-Yan1; Wang, Jing-Lin1; Sun, Xiao-Hong1 |
| 刊名 | Journal of virology
 |
| 出版日期 | 2011-10-01 |
| 卷号 | 85期号:19页码:9847-9853 |
| ISSN号 | 0022-538X |
| DOI | 10.1128/jvi.00825-11 |
| 通讯作者 | Liang, guo-dong(gdliang@hotmail.com) |
| 英文摘要 | Japanese encephalitis virus (jev), a mosquito-borne zoonotic pathogen, is one of the major causes of viral encephalitis worldwide. previous phylogenetic studies based on the envelope protein indicated that there are four genotypes, and surveillance data suggest that genotype i is gradually replacing genotype iii as the dominant strain. here we report an evolutionary analysis based on 98 full-length genome sequences of jev, including 67 new samples isolated from humans, pigs, mosquitoes, midges. and bats in affected areas. to investigate the relationships between the genotypes and the significance of genotype i in recent epidemics, we estimated evolutionary rates, ages of common ancestors, and population demographics. our results indicate that the genotypes diverged in the order iv, iii, ii, and i and that the genetic diversity of genotype iii has decreased rapidly while that of genotype i has increased gradually, consistent with its emergence as the dominant genotype. |
| WOS关键词 | FREQUENT INTRODUCTIONS ; SOUTHEAST-ASIA ; EAST-ASIA ; CHINA ; OUTBREAK ; AUSTRALIA ; INDIA |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000296253900018 |
| 出版者 | AMER SOC MICROBIOLOGY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2375917 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Liang, Guo-Dong |
| 作者单位 | 1.Chinese Ctr Dis Control & Prevent, Inst Viral Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing 100052, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, Bioinformat Grp, State Key Lab Virol, Wuhan 430071, Hubei, Peoples R China 3.Yunnan Inst Endem Dis Control & Prevent, Dali 671000, Yunnan, Peoples R China 4.Natl Inst Infect Dis, Shinjuku Ku, Tokyo 1628640, Japan |
| 推荐引用方式 GB/T 7714 | Pan, Xiao-Ling,Liu, Hong,Wang, Huan-Yu,et al. Emergence of genotype i of japanese encephalitis virus as the dominant genotype in asia[J]. Journal of virology,2011,85(19):9847-9853. |
| APA | Pan, Xiao-Ling.,Liu, Hong.,Wang, Huan-Yu.,Fu, Shi-Hong.,Liu, Hai-Zhou.,...&Liang, Guo-Dong.(2011).Emergence of genotype i of japanese encephalitis virus as the dominant genotype in asia.Journal of virology,85(19),9847-9853. |
| MLA | Pan, Xiao-Ling,et al."Emergence of genotype i of japanese encephalitis virus as the dominant genotype in asia".Journal of virology 85.19(2011):9847-9853. |
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来源：武汉病毒研究所
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