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Genetic organization of the hindiii-i region of the single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria

文献类型:期刊论文

作者Hu, ZH; Arif, BM; Sun, JS; Chen, XW; Zuidema, D; Goldbach, RW; Vlak, JM
刊名Virus research
出版日期1998-05-01
卷号55期号:1页码:71-82
关键词Buzura suppressaria Single-nucleocapsid nucleopolyhedrovirus Gene arrangement Ctl Lap Sod Phylogeny
ISSN号0168-1702
通讯作者Vlak, jm()
英文摘要In order to investigate the genomic organization of the single-nucleocapsid nucleopolyhedrovirus (snpv) of buzura suppressaria (busunpv), the hindiii-i fragment located at map units (mu) 26.6-29.4 of the viral genome was sequenced. the fragment contained two partial and three complete open reading frames (orfs) representing the 3' end of a polyhedron envelope protein gene (pep), a homologue of the acmnpv orf117, a conotoxin-like protein gene (ctl), an inhibitor of apoptosis gene (iap) and a superoxide dismutase gene (sod), respectively. these five genes were identified for the first time in a snpv. sequence analysis further revealed that these orfs have the same conserved motifs and gene structure as those observed in their homologues from other baculoviruses. between ctl and lap, an intergenic region of about 700 basepairs with structure similar to non-hr origins of dna replication was observed. the genomic arrangement of the orfs in the busunpv hindiii-i fragment is very different from the arrangement of their homologues in the genome of autographa californica multiple nucleocapsid (m) npv and other baculoviruses to date. our data suggest that on the basis of gene arrangement, busunpv belongs to a distinct taxon within the baculoviridae family, corroborating our previous conclusions derived from phylogeny analysis of several busunpv genes. (c) 1998 elsevier science b.v. all rights reserved.
WOS关键词NUCLEAR POLYHEDROSIS-VIRUS ; ERYTHROCYTE SUPEROXIDE-DISMUTASE ; NUCLEOTIDE-SEQUENCE ; ENVELOPE PROTEIN ; ORGYIA-PSEUDOTSUGATA ; BACULOVIRUS GENE ; DNA-REPLICATION ; LOCALIZATION ; APOPTOSIS ; MOTIF
WOS研究方向Virology
WOS类目Virology
语种英语
WOS记录号WOS:000075203000007
出版者ELSEVIER SCIENCE BV
URI标识http://www.irgrid.ac.cn/handle/1471x/2376034
专题武汉病毒研究所
通讯作者Vlak, JM
作者单位1.Agr Univ Wageningen, Dept Virol, NL-6709 PD Wageningen, Netherlands
2.Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430071, Peoples R China
3.Forestry Canada, Inst Forest Pest Management, Sault St Marie, ON P6A 5M7, Canada
推荐引用方式
GB/T 7714
Hu, ZH,Arif, BM,Sun, JS,et al. Genetic organization of the hindiii-i region of the single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria[J]. Virus research,1998,55(1):71-82.
APA Hu, ZH.,Arif, BM.,Sun, JS.,Chen, XW.,Zuidema, D.,...&Vlak, JM.(1998).Genetic organization of the hindiii-i region of the single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria.Virus research,55(1),71-82.
MLA Hu, ZH,et al."Genetic organization of the hindiii-i region of the single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria".Virus research 55.1(1998):71-82.

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来源:武汉病毒研究所

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