Immunomodulating components from chinese medicines
文献类型：期刊论文
| 作者 | Li, XY |
| 刊名 | Pharmaceutical biology
 |
| 出版日期 | 2000 |
| 卷号 | 38页码:33-40 |
| 关键词 | Acanthopanax senticosus Achyranthes bidentata Astragalus mongholicus Chinese medicine Coriolus versicolor Immunomodulator Ginkgo biloba Polysaccharide Terpene Tripterygium wilfordii |
| ISSN号 | 1388-0209 |
| 通讯作者 | Li, xy(xyli@mail.shcnc.ac.cn) |
| 英文摘要 | Modern scientific studies have shown that several components from chinese herbal medicines are immunologically active. astragalus mongholicus polysaccharide aps, a polymer of glucose and arabinose, increases specific antibody formation as well as synthesis of rna, dna and protein in mouse spleen. the polysaccharide pes isolated from acanthopanax senticosus used as a tonic and sedative agent also induces interferon production. an oligosaccharide abps isolated from achyranthes bidentala with a mw of only 1360 da significantly enhances the humoral immune response and antagonizes the immunosuppressive effects of cyclosporin a. abps increases the production of tnf and the activity of nk cells. in tumor patients treated by chemotherapy or radiotherapy, abps maintained their peripheral white blood cell count and improved the quality of life. psp, the protein bound polysaccharide extracted from coriolus versicolor, has been developed as an anticancer drug in china. it promoted t cell proliferation, increased nk and lak cell activities as well as anticancer cytokines il-2, il-6, ifn-gamma and tnf-alpha production so as to induce tumor cell apoptosis. celastrol, a triterpene compound isolated from tripterygium wilfordii was proven to be an equally-strong immunosuppressor and inhibited free radical damage in experimental arthritis. ginkgo biloba extract improves cognitive functions. gingkolide a and b inhibited il-1, tnf-alpha and nitric oxide production in rat microglia and prevented the chronic inflammatory process in neurodegenerative diseases. |
| WOS关键词 | NITRIC-OXIDE PRODUCTION ; LIPOPOLYSACCHARIDES IN-VITRO ; CELLS |
| WOS研究方向 | Plant Sciences ; Medical Laboratory Technology ; Pharmacology & Pharmacy |
| WOS类目 | Plant Sciences ; Medical Laboratory Technology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000166795000005 |
| 出版者 | INFORMA HEALTHCARE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376093 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Li, XY |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Dept Pharmacol, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, XY. Immunomodulating components from chinese medicines[J]. Pharmaceutical biology,2000,38:33-40. |
| APA | Li, XY.(2000).Immunomodulating components from chinese medicines.Pharmaceutical biology,38,33-40. |
| MLA | Li, XY."Immunomodulating components from chinese medicines".Pharmaceutical biology 38(2000):33-40. |
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来源：武汉病毒研究所
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