One-pot to synthesize multifunctional carbon dots for near infrared fluorescence imaging and photothermal cancer therapy
文献类型：期刊论文
| 作者 | Zheng, Min1,2; Li, Yang2; Liu, Shi2; Wang, Weiqi2,3; Xie, Zhigang2; Jing, Xiabin2 |
| 刊名 | Acs applied materials & interfaces
 |
| 出版日期 | 2016-09-14 |
| 卷号 | 8期号:36页码:23533-23541 |
| 关键词 | Carbon dots Near-infrared photothermal therapy Bioimaging Theranostic Cyanine |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/acsami.6b07453 |
| 通讯作者 | Xie, zhigang(xiez@ciac.ac.cn) |
| 英文摘要 | It is an emerging, focus to develop a simple and straightforward strategy to synthesize multifunctional nanomedicines for cancer imaging and treatment. in this work, a new carbon dot (named cycd) with intrinsic theranostic properties was prepared from a hydrophobic cyanine dye [2-((e)-2((e)-2-chloro-3-((e)-2-(1-(2-hydroxyethyl)-3,3-dimethylindolin-2-ylidene) ethylidene)cyclohex-1-en-1-yl)vinyl)-1-(2-hydroxyethyl)-3,3-dimethyl-3h-indol-1-ium iodide, cyoh] and poly(ethylene glycol) (peg800) via a simple solvothermal process. the as-prepared cycd is,well dispersed in water media with an average diameter of 2.9 +/- 0.5 nm; it possesses favorable hydrophilicity and excellent photostability. more importantly, the strong absorption and near-ir (nir) emission within the range from 600 to 900 nm, along with preferential;uptake at tumors and high photothermal conversion efficienecy (eta = 38.7%), facilitate cycd to act as an ideal theranostic agent for nir fluorescent imaging and photothermal therapy in vitro, and in vivo. this work highlights theranostic cds as an excellent candidate for efficient canter imaging and therapy. |
| WOS关键词 | GRAPHENE QUANTUM DOTS ; FULL-COLOR EMISSION ; PHOTODYNAMIC THERAPY ; IN-VIVO ; HIGHLY LUMINESCENT ; GOLD NANOPARTICLES ; FUTURE PERSPECTIVE ; GREEN SYNTHESIS ; DRUG-DELIVERY ; CYANINE DYES |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| WOS类目 | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000383412000012 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376179 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Xie, Zhigang |
| 作者单位 | 1.Changchun Univ Technol, Adv Inst Mat Sci, Chem & Life Sci Sch, 2055 Yanan St, Changchun 130012, Jilin, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Min,Li, Yang,Liu, Shi,et al. One-pot to synthesize multifunctional carbon dots for near infrared fluorescence imaging and photothermal cancer therapy[J]. Acs applied materials & interfaces,2016,8(36):23533-23541. |
| APA | Zheng, Min,Li, Yang,Liu, Shi,Wang, Weiqi,Xie, Zhigang,&Jing, Xiabin.(2016).One-pot to synthesize multifunctional carbon dots for near infrared fluorescence imaging and photothermal cancer therapy.Acs applied materials & interfaces,8(36),23533-23541. |
| MLA | Zheng, Min,et al."One-pot to synthesize multifunctional carbon dots for near infrared fluorescence imaging and photothermal cancer therapy".Acs applied materials & interfaces 8.36(2016):23533-23541. |
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来源：中国科学院大学
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