Dietary fat intake and endometrial cancer risk a dose response meta-analysis
文献类型：期刊论文
| 作者 | Zhao, Jing1; Lyu, Chen1,2; Gao, Jian3; Du, Li1,4; Shan, Boer5; Zhang, Hong4; Wang, Hua-Ying5; Gao, Ying1 |
| 刊名 | Medicine
 |
| 出版日期 | 2016-07-01 |
| 卷号 | 95期号:27页码:8 |
| 关键词 | Dose response Endometrial cancer Linoleic acid Meta-analysis Monounsaturated fatty acids Polyunsaturated fatty acids Saturated fat |
| ISSN号 | 0025-7974 |
| DOI | 10.1097/md.0000000000004121 |
| 通讯作者 | Gao, ying(yinggao@sibs.ac.cn) |
| 英文摘要 | Since body fatness is a convincing risk factor for endometrial cancer, dietary fat intake was speculated to be associated with endometrial cancer risk. however, epidemiological studies are inconclusive. we aimed to conduct a meta-analysis to assess the associations between dietary fat intake and endometrial cancer risk. we searched the pubmed, embase, and web of science databases updated to september 2015. in total, 7 cohort and 14 case-control studies were included. pooled analysis of case-control studies suggested that endometrial cancer risk was significantly increased by 5% per 10% kilocalories from total fat intake (p=0.02) and by 17% per 10g/1000 kcal of saturated fat intake (p<0.001). summary of 3 cohort studies showed significant inverse association between monounsaturated fatty acids and endometrial cancer risk (odds ratio=0.84, 95% confidence interval=0.73-0.98) with a total of 524583 participants and 3503 incident cases. no significant associations were found for polyunsaturated fatty acids and linoleic acid. in conclusion, positive associations with endometrial cancer risk were observed for total fat and saturated fat intake in the case-control studies. results from the cohort studies suggested higher monounsaturated fatty acids intake was significantly associated with lower endometrial cancer risk. |
| WOS关键词 | EPIDEMIOLOGIC EVIDENCE ; POSTMENOPAUSAL WOMEN ; NUTRITIONAL FACTORS ; UNITED-STATES ; ASSOCIATION ; COHORT ; ACID ; HEALTH ; OMEGA-3-FATTY-ACIDS ; SECRETION |
| WOS研究方向 | General & Internal Medicine |
| WOS类目 | Medicine, General & Internal |
| 语种 | 英语 |
| WOS记录号 | WOS:000380372400066 |
| 出版者 | LIPPINCOTT WILLIAMS & WILKINS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376349 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Gao, Ying |
| 作者单位 | 1.Univ Chinese Acad Sci, Shanghai Inst Biol Sci, Chinese Acad Sci, Key Lab Nutr & Metab,Inst Nutr Sci, Shanghai, Peoples R China 2.Indiana Univ, Dept Appl Hlth Sci, Sch Publ Hlth, Bloomington, IN 47405 USA 3.Fudan Univ, Zhongshan Hosp, Dept Nutr, Shanghai, Peoples R China 4.Fudan Univ, Inst Biostat, Shanghai, Peoples R China 5.Fudan Univ, Shanghai Canc Ctr, Dept Gynecol Oncol, Dept Oncol,Shanghai Med Coll, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jing,Lyu, Chen,Gao, Jian,et al. Dietary fat intake and endometrial cancer risk a dose response meta-analysis[J]. Medicine,2016,95(27):8. |
| APA | Zhao, Jing.,Lyu, Chen.,Gao, Jian.,Du, Li.,Shan, Boer.,...&Gao, Ying.(2016).Dietary fat intake and endometrial cancer risk a dose response meta-analysis.Medicine,95(27),8. |
| MLA | Zhao, Jing,et al."Dietary fat intake and endometrial cancer risk a dose response meta-analysis".Medicine 95.27(2016):8. |
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来源：中国科学院大学
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