Cu-catalyzed consecutive hydroxylation and aerobic oxidative cycloetherification under microwave conditions: entry to 2-arylbenzofuran-3-carboxylic acids
文献类型：期刊论文
| 作者 | Xu, Tianlong1,3; Zhang, Ensheng1,3; Wang, Dejian1,3; Wang, Yan4; Zou, Yong2 |
| 刊名 | Journal of organic chemistry
 |
| 出版日期 | 2015-05-01 |
| 卷号 | 80期号:9页码:4313-4324 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/jo502802k |
| 通讯作者 | Zou, yong(zou_jinan@163.com) |
| 英文摘要 | A convenient one-pot synthesis of 2-arylbenzofuran-3-carboxylic acids from (e)-2-(2-bromophenyl)-3-phenylacrylic acids via cu-catalyzed consecutive hydroxylation and aerobic oxidative cycloetherification under microwave conditions has been developed. this protocol employed the reagent combination of cu(oac)(2), 1,10-phen, and koh in dmso/h2o (1:1), all of which are cost-effective, readily available, and easily removable from the reaction mixture. utilizing this synthetic protocol, various 2-arylbenzofuran-3-carboxylic acids as well as the natural product moracin m have been synthesized in satisfactory yields under mild conditions. |
| WOS关键词 | PROSTATE-CANCER CELLS ; METHYL 3-DEHYDROSHIKIMIATE ; MYCOBACTERIUM-TUBERCULOSIS ; MORACIN M ; DERIVATIVES ; INHIBITORS ; ESTERS ; AGENTS ; BENZOFURANS ; STILBENES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000354004600009 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376524 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zou, Yong |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Guangdong, Peoples R China 2.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 4.Second Mil Med Univ, Sch Pharm, New Drug Res & Dev Ctr, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Tianlong,Zhang, Ensheng,Wang, Dejian,et al. Cu-catalyzed consecutive hydroxylation and aerobic oxidative cycloetherification under microwave conditions: entry to 2-arylbenzofuran-3-carboxylic acids[J]. Journal of organic chemistry,2015,80(9):4313-4324. |
| APA | Xu, Tianlong,Zhang, Ensheng,Wang, Dejian,Wang, Yan,&Zou, Yong.(2015).Cu-catalyzed consecutive hydroxylation and aerobic oxidative cycloetherification under microwave conditions: entry to 2-arylbenzofuran-3-carboxylic acids.Journal of organic chemistry,80(9),4313-4324. |
| MLA | Xu, Tianlong,et al."Cu-catalyzed consecutive hydroxylation and aerobic oxidative cycloetherification under microwave conditions: entry to 2-arylbenzofuran-3-carboxylic acids".Journal of organic chemistry 80.9(2015):4313-4324. |
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来源：中国科学院大学
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