Cold exposure inhibits hypothalamic kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male brandt's vole (lasiopodomys brandtii)
文献类型：期刊论文
| 作者 | Zhang, Qiang1,2; Lin, Yi1,3; Zhang, Xue-Ying1; Wang, De-Hua1 |
| 刊名 | International journal of biometeorology
 |
| 出版日期 | 2015-06-01 |
| 卷号 | 59期号:6页码:679-691 |
| 关键词 | Brandt's voles (lasiopodomys brandtii) Cold exposure Kiss-1 Leptin Reproductive development |
| ISSN号 | 0020-7128 |
| DOI | 10.1007/s00484-014-0879-4 |
| 通讯作者 | Wang, de-hua(wangdh@ioz.ac.cn) |
| 英文摘要 | Cold commonly affects growth and reproductive development in small mammals. here, we test the hypothesis that low ambient temperature will affect growth and puberty onset, associated with altered hypothalamic kiss-1 gene expression and serum leptin concentration in wild rodents. male brandt's voles (lasiopodomys brandtii) were exposed to cold (4 +/- 1 degrees c) and warm (23 +/- 1 degrees c) conditions from the birth and sacrificed on different developmental stages (day 26, day 40, day 60, and day 90, respectively). brandt's voles increased the thermogenic capacity of brown adipose tissue, mobilized body fat, decreased serum leptin levels, and delayed the reproductive development especially on day 40 in the cold condition. they increased food intake to compensate for the high energy demands in the cold. the hypothalamic kiss-1 gene expression on day 26 was decreased, associated with lower wet testis mass and testis testosterone concentration on day 40, in the cold-exposed voles compared to that in the warm. serum leptin was positively correlated with body fat, testis mass, and testosterone concentration. these data suggested that cold exposure inhibited hypothalamic kiss-1 gene expression during the early stage of development, decreased serum leptin concentration, and delayed reproductive development in male brandt's voles. |
| WOS关键词 | BROWN ADIPOSE-TISSUE ; BODY-MASS REGULATION ; AMBIENT-TEMPERATURE ; ADAPTIVE THERMOGENESIS ; MICROTUS-BRANDTI ; FEMALE MICE ; SYSTEM ; KISSPEPTIN ; MELATONIN ; WEIGHT |
| WOS研究方向 | Biophysics ; Environmental Sciences & Ecology ; Meteorology & Atmospheric Sciences ; Physiology |
| WOS类目 | Biophysics ; Environmental Sciences ; Meteorology & Atmospheric Sciences ; Physiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000355337300002 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376613 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, De-Hua |
| 作者单位 | 1.Chinese Acad Sci, Inst Zool, State Key Lab Integrated Management Pest Insects, Beijing 100101, Peoples R China 2.Zunyi Normal Coll, Dept Biol, Zunyi 563002, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Qiang,Lin, Yi,Zhang, Xue-Ying,et al. Cold exposure inhibits hypothalamic kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male brandt's vole (lasiopodomys brandtii)[J]. International journal of biometeorology,2015,59(6):679-691. |
| APA | Zhang, Qiang,Lin, Yi,Zhang, Xue-Ying,&Wang, De-Hua.(2015).Cold exposure inhibits hypothalamic kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male brandt's vole (lasiopodomys brandtii).International journal of biometeorology,59(6),679-691. |
| MLA | Zhang, Qiang,et al."Cold exposure inhibits hypothalamic kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male brandt's vole (lasiopodomys brandtii)".International journal of biometeorology 59.6(2015):679-691. |
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来源：中国科学院大学
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