Nor-lignans and steroidal saponins from asparagus gobicus
文献类型：期刊论文
| 作者 | Yang, CX; Huang, SS; Yang, XP; Jia, ZJ |
| 刊名 | Planta medica
 |
| 出版日期 | 2004-05-01 |
| 卷号 | 70期号:5页码:446-451 |
| 关键词 | Asparagus gobicus Asparagaceae Nor-lignans Steroidal saponins Cytotoxic activity |
| ISSN号 | 0032-0943 |
| DOI | 10.1055/s-2004-818974 |
| 通讯作者 | Jia, zj() |
| 英文摘要 | From the roots of asparagus gobicus, four new nor-lignans, 3-methoxynyasin, iso-agatharesinol, gobicusins a, b and one new steroidal saponin, 3-o-[beta-d-xylopyranosyl(1-4)-beta-d-glicopyranosyl(1 -2)-beta-d-glucopyranosyl]-(25s)-5beta-spirostan-3beta-ol (11) were isolated, together with twelve known compounds. the structures of the new compounds were established by spectroscopic methods including 2d-nmr techniques (h-1-h-1 cosy, hmbc, hmqc) and chemical transformations. nyasol (5) and 11 exhibited remarkable in vitro cytotoxic activity against cultured ho-8910 (human ovarian carcinoma) and bel-7402 (human hepatoma) cells with ic50 vales of 30.6 and 29.4 mum, 5.2 and 5.2 mum, respectively. |
| WOS关键词 | GLYCOSIDES ; CURILLUS |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| WOS类目 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000221553200012 |
| 出版者 | GEORG THIEME VERLAG KG |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376907 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Jia, ZJ |
| 作者单位 | Lanzhou Univ, Coll Chem & Chem Engn, Natl Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, CX,Huang, SS,Yang, XP,et al. Nor-lignans and steroidal saponins from asparagus gobicus[J]. Planta medica,2004,70(5):446-451. |
| APA | Yang, CX,Huang, SS,Yang, XP,&Jia, ZJ.(2004).Nor-lignans and steroidal saponins from asparagus gobicus.Planta medica,70(5),446-451. |
| MLA | Yang, CX,et al."Nor-lignans and steroidal saponins from asparagus gobicus".Planta medica 70.5(2004):446-451. |
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来源：中国科学院大学
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