Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells
文献类型:期刊论文
作者 | Huang, SY; Liu, Y; Liang, PJ |
刊名 | Neuroreport
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出版日期 | 2004-10-25 |
卷号 | 15期号:15页码:2311-2315 |
关键词 | Ampa receptor Calcium-induced calcium release Calcium store Dynamic model Horizontal cell |
ISSN号 | 0959-4965 |
通讯作者 | Liang, pj() |
英文摘要 | Fura-2 fluorescent calcium imaging was applied to measure [ca2+](i) in freshly dissociated horizontal cells of carp retina, and a model containing endoplasmic reticulum (er) membrane processes and plasma membrane processes was constructed for quantitative analyses of the ampa-triggered calcium dynamics. a transient increase followed by a sustained steady level of [ca2+](i) was observed when 100 mum ampa was applied, while the initial transient increase of [ca2+](i) was suppressed by exogenously applied ryanodine. the model analyses results suggest that the ampa-triggered calcium dynamics involves a number of cytoplasmic and endoplasmic processes that interact with each other. it also suggests that calcium store is an important part contributing to the transient calcium signal. |
WOS关键词 | INDUCED CALCIUM-RELEASE ; RECEPTORS ; DESENSITIZATION ; MODULATION ; PLASTICITY ; GLUTAMATE ; MEMBRANE ; KINETICS ; NEURONS |
WOS研究方向 | Neurosciences & Neurology |
WOS类目 | Neurosciences |
语种 | 英语 |
WOS记录号 | WOS:000225141700002 |
出版者 | LIPPINCOTT WILLIAMS & WILKINS |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2376936 |
专题 | 中国科学院大学 |
通讯作者 | Liang, PJ |
作者单位 | 1.Shanghai Jiao Tong Univ, Dept Biomed Engn, Shanghai 200030, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Neurobiol, Shanghai 200031, Peoples R China |
推荐引用方式 GB/T 7714 | Huang, SY,Liu, Y,Liang, PJ. Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells[J]. Neuroreport,2004,15(15):2311-2315. |
APA | Huang, SY,Liu, Y,&Liang, PJ.(2004).Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells.Neuroreport,15(15),2311-2315. |
MLA | Huang, SY,et al."Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells".Neuroreport 15.15(2004):2311-2315. |
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来源:中国科学院大学
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