中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells

文献类型:期刊论文

作者Huang, SY; Liu, Y; Liang, PJ
刊名Neuroreport
出版日期2004-10-25
卷号15期号:15页码:2311-2315
关键词Ampa receptor Calcium-induced calcium release Calcium store Dynamic model Horizontal cell
ISSN号0959-4965
通讯作者Liang, pj()
英文摘要Fura-2 fluorescent calcium imaging was applied to measure [ca2+](i) in freshly dissociated horizontal cells of carp retina, and a model containing endoplasmic reticulum (er) membrane processes and plasma membrane processes was constructed for quantitative analyses of the ampa-triggered calcium dynamics. a transient increase followed by a sustained steady level of [ca2+](i) was observed when 100 mum ampa was applied, while the initial transient increase of [ca2+](i) was suppressed by exogenously applied ryanodine. the model analyses results suggest that the ampa-triggered calcium dynamics involves a number of cytoplasmic and endoplasmic processes that interact with each other. it also suggests that calcium store is an important part contributing to the transient calcium signal.
WOS关键词INDUCED CALCIUM-RELEASE ; RECEPTORS ; DESENSITIZATION ; MODULATION ; PLASTICITY ; GLUTAMATE ; MEMBRANE ; KINETICS ; NEURONS
WOS研究方向Neurosciences & Neurology
WOS类目Neurosciences
语种英语
WOS记录号WOS:000225141700002
出版者LIPPINCOTT WILLIAMS & WILKINS
URI标识http://www.irgrid.ac.cn/handle/1471x/2376936
专题中国科学院大学
通讯作者Liang, PJ
作者单位1.Shanghai Jiao Tong Univ, Dept Biomed Engn, Shanghai 200030, Peoples R China
2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Neurobiol, Shanghai 200031, Peoples R China
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GB/T 7714
Huang, SY,Liu, Y,Liang, PJ. Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells[J]. Neuroreport,2004,15(15):2311-2315.
APA Huang, SY,Liu, Y,&Liang, PJ.(2004).Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells.Neuroreport,15(15),2311-2315.
MLA Huang, SY,et al."Role of ca2+ store in ampa-triggered ca2+ dynamics in retinal horizontal cells".Neuroreport 15.15(2004):2311-2315.

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来源:中国科学院大学

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