Promoted electron transfer of mitoxantrone binding with dna by cytochrome c
文献类型：期刊论文
| 作者 | Li, N; Yang, XR |
| 刊名 | Biochemical and biophysical research communications
 |
| 出版日期 | 2005-06-17 |
| 卷号 | 331期号:4页码:947-952 |
| 关键词 | Mitoxantrone Dna Cytochrome c Electron transfer |
| ISSN号 | 0006-291X |
| DOI | 10.1016/j.bbrc.2005.04.018 |
| 通讯作者 | Yang, xr() |
| 英文摘要 | A promoted electron transfer of an antitumor drug, mitoxantrone (mtx), intercalating into dna duplex was successfully obtained upon addition of cytochromes c (cyt. c) in naac-hac buffer solution (ph 4.5). the experimental results suggested that co-existence of mtx and cyt. c in the dna helix is an important factor for accelerated electron transfer of mtx, where the promoter, cyt. c, operated smoothly through the dna bridge. the uv/vis spectroscopic experiments further confirmed the interaction process. furthermore, a possible mechanism of such reaction was also discussed in this paper. (c) 2005 elsevier inc. all rights reserved. |
| WOS关键词 | PEROXIDASE ; COMPLEXES ; FILMS ; STACK |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| WOS类目 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000229234500009 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377030 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Yang, XR |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, N,Yang, XR. Promoted electron transfer of mitoxantrone binding with dna by cytochrome c[J]. Biochemical and biophysical research communications,2005,331(4):947-952. |
| APA | Li, N,&Yang, XR.(2005).Promoted electron transfer of mitoxantrone binding with dna by cytochrome c.Biochemical and biophysical research communications,331(4),947-952. |
| MLA | Li, N,et al."Promoted electron transfer of mitoxantrone binding with dna by cytochrome c".Biochemical and biophysical research communications 331.4(2005):947-952. |
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来源：中国科学院大学
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