Molecular recognition of nucleic acids: coralyne binds strongly to poly(a)
文献类型：期刊论文
| 作者 | Xing, FF; Song, GT; Ren, JS; Chaires, JB; Qu, XG |
| 刊名 | Febs letters
 |
| 出版日期 | 2005-09-12 |
| 卷号 | 579期号:22页码:5035-5039 |
| 关键词 | Dna Rna Dialysis Binding Single-stranded poly(a) Secondary structure |
| ISSN号 | 0014-5793 |
| DOI | 10.1016/j.febslet.2005.07.091 |
| 通讯作者 | Ren, js() |
| 英文摘要 | The small molecule coralyne was found to bind preferentially and strongly to single-stranded poly(a) with an apparent association constant (k-a) of (1.8 +/- 0.3) x 10(6) m-1. binding of coralyne to poly(a) is predominantly enthalpically driven with a stoichiometry of one coralyne per four adenine bases. poly(a) forms a coralyne dependent secondary structure with a melting temperature of 60 degrees c, for the conditions of our study. (c) 2005 federation of european biochemical societies. published by elsevier b.v. all rights reserved. |
| WOS关键词 | DRUG-DNA INTERACTIONS ; RNA-PROCESSING ENZYME ; TARGETING RNA ; STRUCTURAL SELECTIVITY ; INTERCALATION ; ENERGETICS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics ; Cell Biology |
| WOS类目 | Biochemistry & Molecular Biology ; Biophysics ; Cell Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000231837800021 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377118 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Ren, JS |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, Key Lab Rare Earth Chem & Phys, Changchun 130022, Jilin, Peoples R China 2.Univ Louisville, James Graham Brown Canc Ctr, Louisville, KY 40202 USA |
| 推荐引用方式 GB/T 7714 | Xing, FF,Song, GT,Ren, JS,et al. Molecular recognition of nucleic acids: coralyne binds strongly to poly(a)[J]. Febs letters,2005,579(22):5035-5039. |
| APA | Xing, FF,Song, GT,Ren, JS,Chaires, JB,&Qu, XG.(2005).Molecular recognition of nucleic acids: coralyne binds strongly to poly(a).Febs letters,579(22),5035-5039. |
| MLA | Xing, FF,et al."Molecular recognition of nucleic acids: coralyne binds strongly to poly(a)".Febs letters 579.22(2005):5035-5039. |
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来源：中国科学院大学
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