Ca2+-permeable and ca2+-impermeable ampa receptors coexist on horizontal cells
文献类型：期刊论文
| 作者 | Huang, SY; Liang, PJ |
| 刊名 | Neuroreport
 |
| 出版日期 | 2005-02-28 |
| 卷号 | 16期号:3页码:263-266 |
| 关键词 | Ampa receptor Calcium imaging Horizontal cell Joro spider toxin Pentobarbital |
| ISSN号 | 0959-4965 |
| 通讯作者 | Liang, pj() |
| 英文摘要 | Fura-2 fluorescent calcium imaging was used for analyzing the subtype of ampa receptors in freshly dissociated horizontal cells of carp retina. exogenous application of ampa induced an increase of intracellular concentration of free ca2+ ([ca2+](i)) in horizontal cells, while the [ca2+](i) increase was partly inhibited by nifedipine. the residual [ca2+](i) increase was completely eliminated by joro spider toxin-3, a blocker of ca2+-permeable ampa receptors. on the other hand, the application of pentobarbital, which blocked ca2+-impermeable ampa receptors, could also partly inhibit the increase of [ca2+](i), implying that the application of ampa induced the activation of both ca2+-permeable and ca2+-impermeable ampa receptors and the consequent activation of voltage-gated ca2+ channels. taken together, these results suggested that ca2+-permeable and ca2+-impermeable ampa receptors were coexpressed on horizontal cells. (c) 2005 lippincott williams f wilkins. |
| WOS关键词 | GOLDFISH RETINA ; CA2+ PERMEABILITY ; SPIDER TOXIN ; SUBUNIT ; CHANNELS ; ACID ; INTERNEURONS ; SENSITIVITY ; DETERMINES ; NEURONS |
| WOS研究方向 | Neurosciences & Neurology |
| WOS类目 | Neurosciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000227620100012 |
| 出版者 | LIPPINCOTT WILLIAMS & WILKINS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377132 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Liang, PJ |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Dept Biomed Engn, Shanghai 200030, Peoples R China 2.Chinese Acad Sci, Grad Sch Sci, Shanghai Inst Biol Sci, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, SY,Liang, PJ. Ca2+-permeable and ca2+-impermeable ampa receptors coexist on horizontal cells[J]. Neuroreport,2005,16(3):263-266. |
| APA | Huang, SY,&Liang, PJ.(2005).Ca2+-permeable and ca2+-impermeable ampa receptors coexist on horizontal cells.Neuroreport,16(3),263-266. |
| MLA | Huang, SY,et al."Ca2+-permeable and ca2+-impermeable ampa receptors coexist on horizontal cells".Neuroreport 16.3(2005):263-266. |
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来源：中国科学院大学
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