Oxazine 170 induces dna : rna : dna triplex formation
文献类型：期刊论文
| 作者 | Song, GT; Xing, FF; Qu, XG; Chaires, JB; Ren, JS |
| 刊名 | Journal of medicinal chemistry
 |
| 出版日期 | 2005-05-19 |
| 卷号 | 48期号:10页码:3471-3473 |
| ISSN号 | 0022-2623 |
| DOI | 10.1021/jm050131g |
| 通讯作者 | Ren, js() |
| 英文摘要 | The oxazine dye (oxazine 170) was found to induce formation of a hybrid triplex structure, poly ra:(poly dt)(2), under solution conditions in which the triplex would not otherwise form. formation of the hybrid triplex is driven by the structural selective binding of oxazine 170 to poly ra:(poly dt)(2). oxazine 170 serves as a lead compound for the design of new compounds that can modulate triplex formation. |
| WOS关键词 | GENE-EXPRESSION ; LIGAND-BINDING ; NUCLEIC-ACIDS/ ; HYBRID TRIPLEX ; STABILITY ; HELICES ; OLIGONUCLEOTIDES ; RECOGNITION ; SEQUENCE ; DESIGN |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Chemistry, Medicinal |
| 语种 | 英语 |
| WOS记录号 | WOS:000229129700004 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377298 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Ren, JS |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Rare Earth Chem & Phys, Grad Sch, Changchun 130022, Peoples R China 2.Univ Louisville, James Graham Brown Canc Ctr, Louisville, KY 40202 USA |
| 推荐引用方式 GB/T 7714 | Song, GT,Xing, FF,Qu, XG,et al. Oxazine 170 induces dna : rna : dna triplex formation[J]. Journal of medicinal chemistry,2005,48(10):3471-3473. |
| APA | Song, GT,Xing, FF,Qu, XG,Chaires, JB,&Ren, JS.(2005).Oxazine 170 induces dna : rna : dna triplex formation.Journal of medicinal chemistry,48(10),3471-3473. |
| MLA | Song, GT,et al."Oxazine 170 induces dna : rna : dna triplex formation".Journal of medicinal chemistry 48.10(2005):3471-3473. |
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来源：中国科学院大学
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