Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators
文献类型：期刊论文
| 作者 | Ji, QG; Gao, H; Wang, J; Yang, CC; Hui, X; Yan, XM; Wu, XH; Xie, YY; Wang, MW |
| 刊名 | Bioorganic & medicinal chemistry letters
 |
| 出版日期 | 2005-06-02 |
| 卷号 | 15期号:11页码:2891-2893 |
| 关键词 | Serm Benzotbieno[3,2-b]indole Estrogen receptor |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmel.2005.03.011 |
| 通讯作者 | Yang, cc() |
| 英文摘要 | A series of estrogen receptor ligands based on benzothieno[3,2-b]indole were synthesized and their binding affinity for estrogen receptor subtypes (er alpha and er beta) and effects on mouse uterus and bone were evaluated. some of these compounds showed strong binding affinity to er and significantly increased the bone mineral density of ovariectomized mice. (c) 2005 elsevier ltd. all rights reserved. |
| WOS关键词 | SERMS |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| WOS类目 | Chemistry, Medicinal ; Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000229665600039 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377324 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Yang, CC |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Shanghai Inst Mat Med, Shanghai Inst Biol Sci,State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, QG,Gao, H,Wang, J,et al. Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators[J]. Bioorganic & medicinal chemistry letters,2005,15(11):2891-2893. |
| APA | Ji, QG.,Gao, H.,Wang, J.,Yang, CC.,Hui, X.,...&Wang, MW.(2005).Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators.Bioorganic & medicinal chemistry letters,15(11),2891-2893. |
| MLA | Ji, QG,et al."Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators".Bioorganic & medicinal chemistry letters 15.11(2005):2891-2893. |
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来源：中国科学院大学
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