Study of fibrinogen adsorption on self-assembled monolayers on au(111) by atomic force microscopy
文献类型：期刊论文
| 作者 | Lin, Y; Wang, J; Wan, LJ; Fang, XH |
| 刊名 | Ultramicroscopy
 |
| 出版日期 | 2005-11-01 |
| 卷号 | 105期号:1-4页码:129-136 |
| 关键词 | Atomic force microscopy (afm) Fibrinogen Self-assembled monolayer (sam) Haemocompatibility |
| ISSN号 | 0304-3991 |
| DOI | 10.1016/j.ultramic.2005.06.028 |
| 通讯作者 | Fang, xh() |
| 英文摘要 | The adsorption of plasma protein fibrinogen on the self-assembled monolayers (sams) of n-hexadecyl mercaptan and citrate was investigated with atomic force microscopy (afm). on the basis of the preparation of these two flat sams on au(111), high-resolution afm images of bovine fibrinogen were obtained with different protein concentrations. the results indicated that the surface chemical composition significantly affected the adsorption behavior of fibrinogen. since fibrinogen plays a key role in the regulation of both haemostasis and thrombosis, high-resolution afm imaging on sams is expected to be an effective approach to study the haernocompatibility of materials with different surface chemistry. (c) 2005 elsevier b.v. all rights reserved. |
| WOS关键词 | CONFORMATIONAL-CHANGES ; PROTEIN FIBRINOGEN ; AQUEOUS CONDITIONS ; SURFACE ; CITRATE ; BIOMATERIALS ; POLYMERS ; MODE ; GOLD |
| WOS研究方向 | Microscopy |
| WOS类目 | Microscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000233317300021 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377479 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Fang, XH |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Y,Wang, J,Wan, LJ,et al. Study of fibrinogen adsorption on self-assembled monolayers on au(111) by atomic force microscopy[J]. Ultramicroscopy,2005,105(1-4):129-136. |
| APA | Lin, Y,Wang, J,Wan, LJ,&Fang, XH.(2005).Study of fibrinogen adsorption on self-assembled monolayers on au(111) by atomic force microscopy.Ultramicroscopy,105(1-4),129-136. |
| MLA | Lin, Y,et al."Study of fibrinogen adsorption on self-assembled monolayers on au(111) by atomic force microscopy".Ultramicroscopy 105.1-4(2005):129-136. |
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来源：中国科学院大学
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