Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode
文献类型：期刊论文
| 作者 | Sun, JY; Zheng, CY; Xiao, XL; Niu, L; You, TY; Wang, EK |
| 刊名 | Electroanalysis
 |
| 出版日期 | 2005-09-01 |
| 卷号 | 17期号:18页码:1675-1680 |
| 关键词 | Electrochemical detection Capillary electrophoresis Carbon fiber microdisk electrode Methimazole |
| ISSN号 | 1040-0397 |
| DOI | 10.1002/elan.200403272 |
| 通讯作者 | You, ty() |
| 英文摘要 | We developed a sensitive, simple and low cost method to determine methimazole based on capillary electrophoresis with electrochemical detection (ce-ec) at a carbon fiber microdisk electrode (cfe). we investigated the effects of detection potential, the concentration and ph value of the phosphate buffer, and injection time as well as separation voltage on the detection of methimazole. under the optimized conditions: the detection potential at 1.30 v, 10 mmol/l phosphate buffer (ph 7.0), injection time 30 s at a height of 20 centimeter and separation voltage at 15 kv, the linear range was obtained from 1.0 x 10(-7) to 2.0 x 10(-4) mol/l, covering 3 orders of magnitude with a correlation coefficient of 0.9995. the lod (s/n 3) obtained was 5.0 x 10(-8) mol/l. the rsd of migration time and peak current for 2.0 x 10(-4) mol/l methimazole was 1.04% and 1.54% (n = 10), respectively. the method was also used to analyze methimazole tablets and human urine sample. |
| WOS关键词 | SIMPLIFIED AMPEROMETRIC DETECTION ; DOPED DIAMOND ELECTRODE ; FLOW-INJECTION ; CARBIMAZOLE ; SEPARATION ; CHIPS ; IMMUNOASSAYS ; GLUCOSE |
| WOS研究方向 | Chemistry ; Electrochemistry |
| WOS类目 | Chemistry, Analytical ; Electrochemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000232407100010 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377538 |
| 专题 | 中国科学院大学 |
| 通讯作者 | You, TY |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Changchun 130022, Peoples R China 3.Heilongjiang Univ, Life Sci Coll, Harbin 150080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, JY,Zheng, CY,Xiao, XL,et al. Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode[J]. Electroanalysis,2005,17(18):1675-1680. |
| APA | Sun, JY,Zheng, CY,Xiao, XL,Niu, L,You, TY,&Wang, EK.(2005).Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode.Electroanalysis,17(18),1675-1680. |
| MLA | Sun, JY,et al."Electrochemical detection of methimazole by capillary electrophoresis at a carbon fiber microdisk electrode".Electroanalysis 17.18(2005):1675-1680. |
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来源：中国科学院大学
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