Fabrication and characterization of beta-dicalcium silicate/poly(d,l-lactic acid) composite scaffolds
文献类型：期刊论文
| 作者 | Cheng, W; Li, HY; Chang, J |
| 刊名 | Materials letters
 |
| 出版日期 | 2005-07-01 |
| 卷号 | 59期号:17页码:2214-2218 |
| 关键词 | Polymer Beta-dicalcium silicate Composite materials Bioactivity Hydrophilicity |
| ISSN号 | 0167-577X |
| DOI | 10.1016/j.matlet.2005.02.069 |
| 通讯作者 | Chang, j() |
| 英文摘要 | In this paper, poly (d,l-lactic acid) (pdlla) incorporated with bioactive beta-dicalcium silicate (beta-ca2sio4) powders to prepare composite scaffolds through conventional solvent casting-particle leaching method using sodium chloride as porogen. the pore structures and morphology of the scaffolds were determined by scanning electron microscopy (sem) and the porosity of the scaffolds was measured by archimedes's method. the bioactivity of the composite scaffolds were evaluated by soaking in simulated body fluid (sbf) for 7 days and the formation of hydroxyapatite (hap) on the surface was determined by sem and electron dispersive spectrometry (eds). the results showed that the composite scaffolds could induce the formation of hap on their surface after immersion in sbf for 7 days. in addition the hydropbilicity was characterized by measuring the water contact angles of the composite and the results indicated that the addition of beta-ca2sio4 particles could improve the hydrophilicity and the increase of hydrophilicity, could be obtained by the increase of the content of beta-ca2sio4 particles. our studies suggested that the combination of pdlla with bioactive beta-ca2sio4 could take advantage of the bioactivity and hydrophilicity of beta-ca2sio4 and might be a promising approach to obtain composite scaffolds with improved properties. (c) 2005 elsevier b.v. all rights reserved. |
| WOS关键词 | HUMAN-ENDOTHELIAL CELLS ; SIMULATED BODY-FLUID ; POLY(L-LACTIC ACID) ; IN-VITRO ; BIOACTIVITY ; SURFACE ; GLASS ; CULTURE ; FOAMS ; BONE |
| WOS研究方向 | Materials Science ; Physics |
| WOS类目 | Materials Science, Multidisciplinary ; Physics, Applied |
| 语种 | 英语 |
| WOS记录号 | WOS:000229379000027 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377658 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chang, J |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, W,Li, HY,Chang, J. Fabrication and characterization of beta-dicalcium silicate/poly(d,l-lactic acid) composite scaffolds[J]. Materials letters,2005,59(17):2214-2218. |
| APA | Cheng, W,Li, HY,&Chang, J.(2005).Fabrication and characterization of beta-dicalcium silicate/poly(d,l-lactic acid) composite scaffolds.Materials letters,59(17),2214-2218. |
| MLA | Cheng, W,et al."Fabrication and characterization of beta-dicalcium silicate/poly(d,l-lactic acid) composite scaffolds".Materials letters 59.17(2005):2214-2218. |
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来源：中国科学院大学
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