Quantification of several monohydroxylated metabolites of polycyclic aromatic hydrocarbons in urine by high-performance liquid chromatography with fluorescence detection
文献类型：期刊论文
| 作者 | Wang, Y; Zhang, WB; Dong, YL; Fan, RF; Sheng, GY; Fu, JM |
| 刊名 | Analytical and bioanalytical chemistry
 |
| 出版日期 | 2005-11-01 |
| 卷号 | 383期号:5页码:804-809 |
| 关键词 | Polycyclic aromatic hydrocarbons Metabolite Urine High-performance liquid chromatography Solid phase extraction |
| ISSN号 | 1618-2642 |
| DOI | 10.1007/s00216-005-0066-x |
| 通讯作者 | Zhang, wb(zhwb@gig.ac.cn) |
| 英文摘要 | A high-performance liquid chromatographic method with fluorescence detection has been developed to determine the urinary polycyclic aromatic hydrocarbon metabolites 2-hydroxynaphthalene, 2-hydroxyfluorene, 9-hydroxyphenanthrene, 1-hydroxypyrene and 3-hydroxybenz[a]pyrene. solid phase extraction (spe) was used to clean up the samples, and washing with 30% methanol was found to be the best way to remove interferences in the matrix. the method detection limits ranged from 0.044 mu g/l for 1-hydroxypyrene to 1.615 mu g/l for 3-hydroxybenz[a]pyrene, and the recoveries ranged between 40% for 3-hydroxybenz[a]pyrene and 99% for 2-hydroxynaphthalene. the within-day relative standard deviation was lowest for 2-hydroxynaphthalene at 0.67% and went up to 2.42% for 3-hydroxybenz[a]pyrene, and the between-day relative standard deviation ranged from 3.84% for 9-hydroxyphenanthrene to 10.42% for 2-hydroxyfluorene. the correlation coefficients were between 0.9962 and 0.9998. the developed method was successfully used to analyze samples from student volunteers in a high school. |
| WOS关键词 | EXPOSED WORKERS ; 1-HYDROXYPYRENE ; PHENANTHRENE ; PYRENE ; PAH ; BIOMARKER |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| WOS类目 | Biochemical Research Methods ; Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000233874900016 |
| 出版者 | SPRINGER HEIDELBERG |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377718 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhang, WB |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Geochem, State Key Lab Organ Geochem, Guangdong Key Lab Environm Protect & Resources Ut, Guangzhou 510640, Guangdong, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Y,Zhang, WB,Dong, YL,et al. Quantification of several monohydroxylated metabolites of polycyclic aromatic hydrocarbons in urine by high-performance liquid chromatography with fluorescence detection[J]. Analytical and bioanalytical chemistry,2005,383(5):804-809. |
| APA | Wang, Y,Zhang, WB,Dong, YL,Fan, RF,Sheng, GY,&Fu, JM.(2005).Quantification of several monohydroxylated metabolites of polycyclic aromatic hydrocarbons in urine by high-performance liquid chromatography with fluorescence detection.Analytical and bioanalytical chemistry,383(5),804-809. |
| MLA | Wang, Y,et al."Quantification of several monohydroxylated metabolites of polycyclic aromatic hydrocarbons in urine by high-performance liquid chromatography with fluorescence detection".Analytical and bioanalytical chemistry 383.5(2005):804-809. |
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来源：中国科学院大学
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