Synthesis of 3-amino-6/8-substituted-1h-pyrazolo[4,3-c]quinolines
文献类型：期刊论文
| 作者 | Qiao, RZ; Zhang, ZY; Zhao, YF |
| 刊名 | Chemical journal of chinese universities-chinese
 |
| 出版日期 | 2005-02-01 |
| 卷号 | 26期号:2页码:250-253 |
| 关键词 | 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 3-amino-6/8-substituted-1h-pyrazolo[4,3-c] quinoline Synthesis Property |
| ISSN号 | 0251-0790 |
| 通讯作者 | Zhao, yf() |
| 英文摘要 | A simple synthesis of 3-amino-6/8-substituted-1h-pyrazolo[4,3-c]quinolines via closed ring reaction of 4-amino-3-aryl-5 mercapto-s-1, 2, 4-triazoles with 1, 4-dihydro-4-oxo-quinoline-3-carboxylic acids in the presence of phosphoryl chloride, followed by the ring-opening reaction in the presence of hydrazine hydrate was described. this novel and straightforward method for the construction the 3-arnino-1h-pyrazolo[4,3-c]quinolines can be carried out under mild conditions by using readily accessible or commercially available inexpensive materials. the new compounds were dertemined by elementary analyses, ir, h-1 nmr and ms spectra. their spectral properities were also discussed. this mothod may represent a potentially useful route to otherwise laboriously accessible condensed pyrazoles, ring systems. with the advantage of economy, a single pot procedure, excellent yields and mild conditions. this condensed pyrazoles can be synthesized on a large scale conveniently and economically. |
| WOS关键词 | CONVENIENT SYNTHESIS ; DERIVATIVES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000226967200014 |
| 出版者 | HIGHER EDUCATION PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377745 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhao, YF |
| 作者单位 | 1.Tsing Hua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem, Minist Educ, Beijing 100084, Peoples R China 2.Beijing Univ Chem Technol, Coll Life Sci & Biotechnol, Beijing 100029, Peoples R China 3.Lanzhou Univ, Coll Chem & Chem Engn, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, RZ,Zhang, ZY,Zhao, YF. Synthesis of 3-amino-6/8-substituted-1h-pyrazolo[4,3-c]quinolines[J]. Chemical journal of chinese universities-chinese,2005,26(2):250-253. |
| APA | Qiao, RZ,Zhang, ZY,&Zhao, YF.(2005).Synthesis of 3-amino-6/8-substituted-1h-pyrazolo[4,3-c]quinolines.Chemical journal of chinese universities-chinese,26(2),250-253. |
| MLA | Qiao, RZ,et al."Synthesis of 3-amino-6/8-substituted-1h-pyrazolo[4,3-c]quinolines".Chemical journal of chinese universities-chinese 26.2(2005):250-253. |
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来源：中国科学院大学
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