Dna damage of germ cell of rat induced by nitrotoluene chemicals
文献类型：期刊论文
| 作者 | Li, Y; Xu, JB; Lin, Z; Sun, ZW; Long, S; Jin, MH; Liu, XM |
| 刊名 | Journal of environmental sciences-china
 |
| 出版日期 | 2005 |
| 卷号 | 17期号:1页码:84-90 |
| 关键词 | Nitrotoluenes Sertoli/germ cell cocultures Scge Genotoxicity |
| ISSN号 | 1001-0742 |
| 通讯作者 | Li, y(yangl@igsnrr.ac.cn) |
| 英文摘要 | 2,4-dinitrotoluene(2,4-dnt) 9 2 6-dinitrotoluene(2,6-dnt) and 4-nitrotoluene(4-nt) are typical pollutants in the songhua river of northeast china. sertoli/germ cell cocultures and single cell gel electrophoresis(scge) are applied to investigate whether they have genotoxicity on dna damage of germ cell of kunming male rat. the results showed that all three nitrotoluene compounds tested could induce dna single-strand breaks of the germ cell. a significant relationship is found between logarithm dose and the degree of dna damage, which implies that 2,4-dnt, 2,6-dnt and 4-nt have genotoxicity and can induce the germ cell dna strand to break in vitro. |
| WOS关键词 | METABOLITES |
| WOS研究方向 | Environmental Sciences & Ecology |
| WOS类目 | Environmental Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000226147000017 |
| 出版者 | SCIENCE CHINA PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377928 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Li, Y |
| 作者单位 | 1.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China 2.NE Normal Univ, Dept Environm Sci, Changchun 130024, Peoples R China 3.Jilin Univ, Sch Publ Hlth, Changchun 130021, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Y,Xu, JB,Lin, Z,et al. Dna damage of germ cell of rat induced by nitrotoluene chemicals[J]. Journal of environmental sciences-china,2005,17(1):84-90. |
| APA | Li, Y.,Xu, JB.,Lin, Z.,Sun, ZW.,Long, S.,...&Liu, XM.(2005).Dna damage of germ cell of rat induced by nitrotoluene chemicals.Journal of environmental sciences-china,17(1),84-90. |
| MLA | Li, Y,et al."Dna damage of germ cell of rat induced by nitrotoluene chemicals".Journal of environmental sciences-china 17.1(2005):84-90. |
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来源：中国科学院大学
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