The chinese traditional medicine 'bushen yinao pian' increased the level of ageing-related gene lrpap-1 expression in the cerebral tissue of accelerated senescence-prone mouse 8/ta
文献类型：期刊论文
| 作者 | Zhang, C; Yang, T; Wang, JG; Liu, GS; Chen, QX |
| 刊名 | Journal of ethnopharmacology
 |
| 出版日期 | 2005-04-08 |
| 卷号 | 98期号:1-2页码:61-65 |
| 关键词 | Chinese traditional medicine Samp8/ta Anti-ageing Gene expression Ddrt-pcr |
| ISSN号 | 0378-8741 |
| DOI | 10.1016/j.jep.2004.12.023 |
| 通讯作者 | Chen, qx() |
| 英文摘要 | The molecular mechanism of the chinese traditional medicine 'bushen yinao pian' (a complex prescription used for clinical anti-ageing in china for over 20 years) is elusive. in this study, the cdna of low-density lipoprotein related-receptor associated protein- 1 (lrpap-1), an ageing-related gene, which functions as a chaperon or escort protein in the intracellular transport of low-density lipoprotein related-receptor, a transporter of amyloid beta protein (a beta p), had been cloned by screening cdna library based on analyzing the gene expression in cerebral tissue between the test and the control accelerated senescence-prone mouse 8/ta (samp8/ta). the result shows that this complex prescription increased the expression level of lrpap-1. it indicated that the chinese traditional medicine 'bushen yinao pian' plays an important role in anti-ageing by increasing lrpap-1 expression level. (c) 2005 elsevier ireland ltd. all rights reserved. |
| WOS关键词 | RECEPTOR-RELATED PROTEIN ; ALZHEIMERS-DISEASE ; BRAIN ; MODEL ; LRP |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
| WOS类目 | Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000228113700007 |
| 出版者 | ELSEVIER SCI IRELAND LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378365 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chen, QX |
| 作者单位 | 1.Chinese Acad Sci, Inst Genet & Dev Biol, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Lingtai Bichen Med Technol Co Ltd, Beijing 100086, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, C,Yang, T,Wang, JG,et al. The chinese traditional medicine 'bushen yinao pian' increased the level of ageing-related gene lrpap-1 expression in the cerebral tissue of accelerated senescence-prone mouse 8/ta[J]. Journal of ethnopharmacology,2005,98(1-2):61-65. |
| APA | Zhang, C,Yang, T,Wang, JG,Liu, GS,&Chen, QX.(2005).The chinese traditional medicine 'bushen yinao pian' increased the level of ageing-related gene lrpap-1 expression in the cerebral tissue of accelerated senescence-prone mouse 8/ta.Journal of ethnopharmacology,98(1-2),61-65. |
| MLA | Zhang, C,et al."The chinese traditional medicine 'bushen yinao pian' increased the level of ageing-related gene lrpap-1 expression in the cerebral tissue of accelerated senescence-prone mouse 8/ta".Journal of ethnopharmacology 98.1-2(2005):61-65. |
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来源：中国科学院大学
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