中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Effects of the "all-fish" growth hormone transgene expression on non-specific immune functions of common carp, cyprinus carpio l.

文献类型:期刊论文

作者Wang, Wen-Bo; Wang, Ya-Ping; Hu, Wei; Li, Ai-Hua; Cai, Tao-Zhen; Zhu, Zuo-Yan; Wang, Jian-Guo
刊名Aquaculture
出版日期2006-09-08
卷号259期号:1-4页码:81-87
关键词"all-fish" growth hormone gene Transgenic fish Growth hormone Non-specific immune functions
ISSN号0044-8486
DOI10.1016/j.aquaculture.2006.05.016
通讯作者Wang, jian-guo(wangjg@ihb.ac.cn)
英文摘要This study investigated non-specific immune functions of the f-2 generation of "all-fish" growth hormone transgenic carp, cyprinus carpio l. lysozyme activity was 145.0 (+/- 30.7) u ml(-1) in the transgenic fish serum and 105.0 (+/- 38.7) u ml(-1) in age-matched non-transgenic control fish serum, a significant difference (p < 0.01). the serum bactericidal activity in the transgenics was significantly higher than that in the controls (p < 0.05), with the percentage serum killing of 59.5% (6.83%) and 50.8% (8.67%), respectively. values for leukocrit and phagocytic percent of macrophages in head kidney were higher in transgenics than controls (p < 0.05). however, the phagocytic indices in the transgenics and the controls were not different. in addition, the mean body weight of the transgenics was 63.4 (6.65) g, much higher than that of the controls [39.2 (+/- 3.30) g, p < 0.01]. the absolute weight of spleen of the transgenics [0.13 (+/- 0.03) g] was higher than that of the controls [0.08 (+/- 0.02) g, p < 0.01]. however, there was no difference in the relative weight of spleen between the transgenics and the controls, with the spleen mass index being 0.21% (+/- 0.02%) and 0.20% (+/- 0.03%), respectively. this study suggests that the "all-fish" growth hormone transgene expression could stimulate not only the growth but also the non-specific immune functions of carp. (c) 2006 published by elsevier b.v.
WOS关键词BREAM SPARUS-AURATA ; RAINBOW-TROUT ; PROLACTIN ; GENE ; GH ; RESPONSES ; CELLS
WOS研究方向Fisheries ; Marine & Freshwater Biology
WOS类目Fisheries ; Marine & Freshwater Biology
语种英语
WOS记录号WOS:000240559500010
出版者ELSEVIER SCIENCE BV
URI标识http://www.irgrid.ac.cn/handle/1471x/2378416
专题中国科学院大学
通讯作者Wang, Jian-Guo
作者单位1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China
2.Jinan Univ, Inst Hydrobiol, Guangzhou 510632, Guangdong, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China
推荐引用方式
GB/T 7714
Wang, Wen-Bo,Wang, Ya-Ping,Hu, Wei,et al. Effects of the "all-fish" growth hormone transgene expression on non-specific immune functions of common carp, cyprinus carpio l.[J]. Aquaculture,2006,259(1-4):81-87.
APA Wang, Wen-Bo.,Wang, Ya-Ping.,Hu, Wei.,Li, Ai-Hua.,Cai, Tao-Zhen.,...&Wang, Jian-Guo.(2006).Effects of the "all-fish" growth hormone transgene expression on non-specific immune functions of common carp, cyprinus carpio l..Aquaculture,259(1-4),81-87.
MLA Wang, Wen-Bo,et al."Effects of the "all-fish" growth hormone transgene expression on non-specific immune functions of common carp, cyprinus carpio l.".Aquaculture 259.1-4(2006):81-87.

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