Synthesis, characterization and drug release of temperature-sensitive plga-peg-plga hydrogel
文献类型：期刊论文
| 作者 | Lin Hao; Tian Hua-Yu; Sun Jing-Ru; Zhuang Xiu-Li; Chen Xue-Si; Li Yue-Sheng; Jing Xia-Bin |
| 刊名 | Chemical journal of chinese universities-chinese
 |
| 出版日期 | 2006-07-01 |
| 卷号 | 27期号:7页码:1385-1388 |
| 关键词 | Peg Plga Hydrogel Temperature-sensitivity Mechanical property Drug release |
| ISSN号 | 0251-0790 |
| 通讯作者 | Chen xue-si(xschen@ciac.jl.cn) |
| 英文摘要 | A series of plga-peg-plgas with m-n =3 000-7 000 were synthesized by rop of l-lactide and glycolide with peg(m-w = 1 000 and 4 600) as the initiators. the dynamic viscoanalyser and phase diagram were utilized to investigate the mechanical properties with sol-gel transition of the hydrogel system, and the g' and g" were between 10(2) and 10(4) pa. also, the fluorescence spectroscopy of plga-peg-plga micelle solution was investigated to reveal the gelation mechanism of hydrogel. finally, the controlled release of ceftazidime from the hydrogel was observed. |
| WOS关键词 | BLOCK-COPOLYMERS ; PLLA |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000239259000050 |
| 出版者 | HIGHER EDUCATION PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378645 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chen Xue-Si |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Chem & Phys, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin Hao,Tian Hua-Yu,Sun Jing-Ru,et al. Synthesis, characterization and drug release of temperature-sensitive plga-peg-plga hydrogel[J]. Chemical journal of chinese universities-chinese,2006,27(7):1385-1388. |
| APA | Lin Hao.,Tian Hua-Yu.,Sun Jing-Ru.,Zhuang Xiu-Li.,Chen Xue-Si.,...&Jing Xia-Bin.(2006).Synthesis, characterization and drug release of temperature-sensitive plga-peg-plga hydrogel.Chemical journal of chinese universities-chinese,27(7),1385-1388. |
| MLA | Lin Hao,et al."Synthesis, characterization and drug release of temperature-sensitive plga-peg-plga hydrogel".Chemical journal of chinese universities-chinese 27.7(2006):1385-1388. |
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来源：中国科学院大学
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