Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics
文献类型:期刊论文
作者 | Du, RL; Chang, J; Ni, SY; Zhai, WY; Wang, JY |
刊名 | Journal of biomaterials applications
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出版日期 | 2006-04-01 |
卷号 | 20期号:4页码:341-360 |
关键词 | Bioactive glass Bioactive glass-ceramic Zinc Mechanical strength Osteoblast |
ISSN号 | 0885-3282 |
DOI | 10.1177/0885328206054535 |
通讯作者 | Chang, j() |
英文摘要 | Zinc-containing glass is prepared by the substitution of cao in 58s bioactive glass with 0.5 and 4wt% zno, and glass-ceramics are obtained by beat-treating the glass at 1200 degrees c. the bending strength and in vitro bioactivity of the glass and glass-ceramics are evaluated. the results indicate that zn promotes the crystallization of sio2 and wollastonite in glass-ceramics, and proper crystallization can enhance the bending strength of the glass-ceramic. the in vitro results show that zno in glass retards the hydroxyapatite (ha) nucleation at the initial stage of simulated body fluid (sbf) soaking, but does not affect the growth of ha after long periods of soaking, and the ionic products of 58s4z glass can stimulate the proliferation of osteoblast at certain concentrations. osteoblasts attach well on both glass samples and glass-ceramic samples, but the high si ion concentration released from glass samples restrains the proliferation of osteoblasts after 3 days of culture. in contrast, osteoblasts show good proliferation on glass-ceramic samples, and zno in glass-ceramics promotes the proliferation rate. the results in this study suggest that the glass and glass-ceramics with different zno content might be used as bioactive bone implant materials in different applications. |
WOS关键词 | CALCIUM-PHOSPHATE ; HUMAN OSTEOBLASTS ; IONIC PRODUCTS ; BONE-FORMATION ; GEL ; PROLIFERATION ; DISSOLUTION ; SURFACE ; EXPRESSION ; MAGNESIUM |
WOS研究方向 | Engineering ; Materials Science |
WOS类目 | Engineering, Biomedical ; Materials Science, Biomaterials |
语种 | 英语 |
WOS记录号 | WOS:000236703300003 |
出版者 | SAGE PUBLICATIONS LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378701 |
专题 | 中国科学院大学 |
通讯作者 | Chang, J |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China 3.E China Normal Univ, Sch Biol Sci, Shanghai 200062, Peoples R China |
推荐引用方式 GB/T 7714 | Du, RL,Chang, J,Ni, SY,et al. Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics[J]. Journal of biomaterials applications,2006,20(4):341-360. |
APA | Du, RL,Chang, J,Ni, SY,Zhai, WY,&Wang, JY.(2006).Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics.Journal of biomaterials applications,20(4),341-360. |
MLA | Du, RL,et al."Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics".Journal of biomaterials applications 20.4(2006):341-360. |
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来源:中国科学院大学
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