中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics

文献类型:期刊论文

作者Du, RL; Chang, J; Ni, SY; Zhai, WY; Wang, JY
刊名Journal of biomaterials applications
出版日期2006-04-01
卷号20期号:4页码:341-360
关键词Bioactive glass Bioactive glass-ceramic Zinc Mechanical strength Osteoblast
ISSN号0885-3282
DOI10.1177/0885328206054535
通讯作者Chang, j()
英文摘要Zinc-containing glass is prepared by the substitution of cao in 58s bioactive glass with 0.5 and 4wt% zno, and glass-ceramics are obtained by beat-treating the glass at 1200 degrees c. the bending strength and in vitro bioactivity of the glass and glass-ceramics are evaluated. the results indicate that zn promotes the crystallization of sio2 and wollastonite in glass-ceramics, and proper crystallization can enhance the bending strength of the glass-ceramic. the in vitro results show that zno in glass retards the hydroxyapatite (ha) nucleation at the initial stage of simulated body fluid (sbf) soaking, but does not affect the growth of ha after long periods of soaking, and the ionic products of 58s4z glass can stimulate the proliferation of osteoblast at certain concentrations. osteoblasts attach well on both glass samples and glass-ceramic samples, but the high si ion concentration released from glass samples restrains the proliferation of osteoblasts after 3 days of culture. in contrast, osteoblasts show good proliferation on glass-ceramic samples, and zno in glass-ceramics promotes the proliferation rate. the results in this study suggest that the glass and glass-ceramics with different zno content might be used as bioactive bone implant materials in different applications.
WOS关键词CALCIUM-PHOSPHATE ; HUMAN OSTEOBLASTS ; IONIC PRODUCTS ; BONE-FORMATION ; GEL ; PROLIFERATION ; DISSOLUTION ; SURFACE ; EXPRESSION ; MAGNESIUM
WOS研究方向Engineering ; Materials Science
WOS类目Engineering, Biomedical ; Materials Science, Biomaterials
语种英语
WOS记录号WOS:000236703300003
出版者SAGE PUBLICATIONS LTD
URI标识http://www.irgrid.ac.cn/handle/1471x/2378701
专题中国科学院大学
通讯作者Chang, J
作者单位1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China
3.E China Normal Univ, Sch Biol Sci, Shanghai 200062, Peoples R China
推荐引用方式
GB/T 7714
Du, RL,Chang, J,Ni, SY,et al. Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics[J]. Journal of biomaterials applications,2006,20(4):341-360.
APA Du, RL,Chang, J,Ni, SY,Zhai, WY,&Wang, JY.(2006).Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics.Journal of biomaterials applications,20(4),341-360.
MLA Du, RL,et al."Characterization and in vitro bioactivity of zinc-containing bioactive glass and glass-ceramics".Journal of biomaterials applications 20.4(2006):341-360.

入库方式: iSwitch采集

来源:中国科学院大学

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。