Dependence of the cytotoxicity of multi-walled carbon nanotubes on the culture medium
文献类型：期刊论文
| 作者 | Zhu, Ying; Ran, Tiecheng; Li, Yuguo; Guo, Jinxue; Li, Wenxin |
| 刊名 | Nanotechnology
 |
| 出版日期 | 2006-09-28 |
| 卷号 | 17期号:18页码:4668-4674 |
| ISSN号 | 0957-4484 |
| DOI | 10.1088/0957-4484/17/18/024 |
| 通讯作者 | Li, wenxin(liwenxin@sinap.ac.cn) |
| 英文摘要 | This study examined the influence of multi-walled carbon nanotubes (mwnts) on the growth of the unicellular protozoan tetrallymena pyriformis. contrary to the findings from most other investigations, our experiment indicated that mwnts stimulated growth of the cells cultured in proteose peptone yeast extract medium (ppy). atomic force microscopy images and thermogravimetric analysis showed the spontaneous formation of peptone-mwnt conjugates in the medium by noncovalent binding. uptake of large amounts of the conjugates by tetrahymena pyriformis was responsible for growth stimulation, evidenced by images with fluorescently labelled peptone. after the ppy medium was replaced by a filtrated pond water medium (fpw), however, inhibition of the growth of cells exposed to mwnts occurred. measurements of the level of malondialdehyde and superoxide dismutase activity demonstrated further that mwnts might be either toxic or nontoxic, depending on the medium used to cultivate tetrahymena pyriformis. the biological effects of the interaction of mwnts with some composites in culture media would be helpful for understanding the mechanisms of the toxicity of carbon nanotubes to living systems. |
| WOS关键词 | PULMONARY TOXICITY ; SINGLE ; TRANSPORTERS ; CELLS ; KERATINOCYTES ; EXPOSURE |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied |
| 语种 | 英语 |
| WOS记录号 | WOS:000241157000024 |
| 出版者 | IOP PUBLISHING LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378758 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Li, Wenxin |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Lab Nanobiol & Med, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Ying,Ran, Tiecheng,Li, Yuguo,et al. Dependence of the cytotoxicity of multi-walled carbon nanotubes on the culture medium[J]. Nanotechnology,2006,17(18):4668-4674. |
| APA | Zhu, Ying,Ran, Tiecheng,Li, Yuguo,Guo, Jinxue,&Li, Wenxin.(2006).Dependence of the cytotoxicity of multi-walled carbon nanotubes on the culture medium.Nanotechnology,17(18),4668-4674. |
| MLA | Zhu, Ying,et al."Dependence of the cytotoxicity of multi-walled carbon nanotubes on the culture medium".Nanotechnology 17.18(2006):4668-4674. |
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来源：中国科学院大学
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