Novel nerve guidance material prepared from bovine aponeurosis
文献类型：期刊论文
| 作者 | Lin, Hang; Chen, Bing; Wang, Bin; Zhao, Yannan; Sun, Wenjie; Dai, Jianwu |
| 刊名 | Journal of biomedical materials research part a
 |
| 出版日期 | 2006-12-01 |
| 卷号 | 79a期号:3页码:591-598 |
| 关键词 | Spinal cord injury Axon regeneration Collagen Aponeurosis Nerve guidance |
| ISSN号 | 1549-3296 |
| DOI | 10.1002/jbm.a.30862 |
| 通讯作者 | Dai, jianwu(jwdai@genetics.ac.cn) |
| 英文摘要 | Spinal cord injury (sci) creates an adverse environment for axon regeneration. as a result, the axons at the injury sites begin to be atrophy, retract and lose their functions. several strategies to promote axon regeneration at the injury site have been tested, but the progress is very limited. one of the major reasons is that the regenerated axons often extend randomly and do not reach the proper place. fabricating linearly ordered materials as nerve guidance would be important to solve such problems. in this study, a novel type of nerve guidance material was prepared from the bovine aponeurosis, which mainly consisted of ordered collagen fibers. the processed material showed good cell compatibility and low immunogenisity. moreover, the processed material guided the neurites outgrowth of in vitro cultured cortical neurons along its fibers. the results suggested that the processed aponeurosis would be a proper nerve guidance biomaterial for sci repair. (c) 2006 wiley periodicals, inc. |
| WOS关键词 | SPINAL-CORD-INJURY ; IN-VIVO BIOCOMPATIBILITY ; AXONAL REGENERATION ; FUNCTIONAL RECOVERY ; ENSHEATHING CELLS ; MECHANICAL-PROPERTIES ; STEM-CELLS ; COLLAGEN ; RAT ; REPAIR |
| WOS研究方向 | Engineering ; Materials Science |
| WOS类目 | Engineering, Biomedical ; Materials Science, Biomaterials |
| 语种 | 英语 |
| WOS记录号 | WOS:000242134700017 |
| 出版者 | WILEY-LISS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378885 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Dai, Jianwu |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Mol Dev Biol, Inst Genet & Dev Biol, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Hang,Chen, Bing,Wang, Bin,et al. Novel nerve guidance material prepared from bovine aponeurosis[J]. Journal of biomedical materials research part a,2006,79a(3):591-598. |
| APA | Lin, Hang,Chen, Bing,Wang, Bin,Zhao, Yannan,Sun, Wenjie,&Dai, Jianwu.(2006).Novel nerve guidance material prepared from bovine aponeurosis.Journal of biomedical materials research part a,79a(3),591-598. |
| MLA | Lin, Hang,et al."Novel nerve guidance material prepared from bovine aponeurosis".Journal of biomedical materials research part a 79a.3(2006):591-598. |
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来源：中国科学院大学
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