Radiolabeling of 1-[n ',n '-bis(2-chloroethyl)-4-aminophenyl]-n-methyl-fullereno-c-60-[1,9-c]pyrrolidine with i-125
文献类型：期刊论文
| 作者 | Ran, Tiecheng; Liu, Ruili; Yin, Juanjuan; Zhu, Jianhua; Li, Wenxin; Li, Qingnuan |
| 刊名 | Journal of radioanalytical and nuclear chemistry
 |
| 出版日期 | 2006-06-01 |
| 卷号 | 268期号:3页码:599-603 |
| ISSN号 | 0236-5731 |
| DOI | 10.1556/jrnc.268.2006.3.22 |
| 通讯作者 | Ran, tiecheng() |
| 英文摘要 | A procedure for labeling of a fullerene derivative 1-[n',n'-bis(2-chloroethyl)-4-aminophenyl]-n-methyl-fullereno-c-50-[1.9-c]pyrrolidine (c-60-c13h18n2cl2) with i-125 is reported. the compound was first iodinated with a large excess of iodine monochloride and then radiolabeled by isotopic exchange with (nai)-i-125 in a toluene-water two-phase system. the dependence of the radiolabeling yield on the reaction temperature and exchange time was examined. the radiolabeling yield of the compound was as high as 94% after heating for 2 hours at 130 degrees c. |
| WOS关键词 | NITROGEN-MUSTARD DERIVATIVES ; BIOLOGICAL APPLICATIONS ; FULLERENES |
| WOS研究方向 | Chemistry ; Nuclear Science & Technology |
| WOS类目 | Chemistry, Analytical ; Chemistry, Inorganic & Nuclear ; Nuclear Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000238843600022 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2379086 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Ran, Tiecheng |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Fudan Univ, Sch Pharm, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ran, Tiecheng,Liu, Ruili,Yin, Juanjuan,et al. Radiolabeling of 1-[n ',n '-bis(2-chloroethyl)-4-aminophenyl]-n-methyl-fullereno-c-60-[1,9-c]pyrrolidine with i-125[J]. Journal of radioanalytical and nuclear chemistry,2006,268(3):599-603. |
| APA | Ran, Tiecheng,Liu, Ruili,Yin, Juanjuan,Zhu, Jianhua,Li, Wenxin,&Li, Qingnuan.(2006).Radiolabeling of 1-[n ',n '-bis(2-chloroethyl)-4-aminophenyl]-n-methyl-fullereno-c-60-[1,9-c]pyrrolidine with i-125.Journal of radioanalytical and nuclear chemistry,268(3),599-603. |
| MLA | Ran, Tiecheng,et al."Radiolabeling of 1-[n ',n '-bis(2-chloroethyl)-4-aminophenyl]-n-methyl-fullereno-c-60-[1,9-c]pyrrolidine with i-125".Journal of radioanalytical and nuclear chemistry 268.3(2006):599-603. |
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来源：中国科学院大学
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