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Adsorption behavior of protein onto siloxane microspheres

文献类型:期刊论文

作者Liu, Bailing; Cao, Shunsheng; Deng, Xiaobo; Li, Songjun; Luo, Rong
刊名Applied surface science
出版日期2006-09-15
卷号252期号:22页码:7830-7836
关键词Siloxane microspheres Bovine serum albumin (bsa) Protein adsorption
ISSN号0169-4332
DOI10.1016/j.apsusc.2005.09.058
通讯作者Liu, bailing(blliuchem@hotmail.com)
英文摘要The siloxane microspheres with core-shell structure (pmma/pmps) (mma, methyl methacrylate; mps, 3-methacryloxypropyl-trimethoxysilane) have been prepared by dispersion polymerization as described in our previous work. in this paper, the developed poly(mma-mps) microspheres, as a carrier, are used to investigate the adsorption behavior of bovine serum albumin (bsa) on them. the langmuir and freundlich models have been applied to describe the adsorption behavior. the experimental results indicated that the presence of pmps evidently increases the adsorption rate and the amount of protein, and it also influences the interaction of bsa molecules. the adsorption of bsa on the poly(mma-mps) microspheres seems to be sensitive to ph and ionic strength. the fittings curves from langmuir and freundlich models showed that the adsorption was actually more complicated than ideal situation because one or more interactions were involved in the process. for understanding the electronic contribution, the zeta potential was used to measure the reactive system before and after protein adsorption. (c) 2005 elsevier b.v. all rights reserved.
WOS关键词BOVINE SERUM-ALBUMIN ; POLYMERIC BIOMATERIALS ; SURFACE MODIFICATION ; IONIC-STRENGTH ; IMMOBILIZATION ; ISOTHERMS ; PARTICLES ; HYDROXYAPATITE ; PROPERTY ; SUPPORTS
WOS研究方向Chemistry ; Materials Science ; Physics
WOS类目Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
语种英语
WOS记录号WOS:000240792100015
出版者ELSEVIER SCIENCE BV
URI标识http://www.irgrid.ac.cn/handle/1471x/2379120
专题中国科学院大学
通讯作者Liu, Bailing
作者单位Chinese Acad Sci, Grad Sch, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China
推荐引用方式
GB/T 7714
Liu, Bailing,Cao, Shunsheng,Deng, Xiaobo,et al. Adsorption behavior of protein onto siloxane microspheres[J]. Applied surface science,2006,252(22):7830-7836.
APA Liu, Bailing,Cao, Shunsheng,Deng, Xiaobo,Li, Songjun,&Luo, Rong.(2006).Adsorption behavior of protein onto siloxane microspheres.Applied surface science,252(22),7830-7836.
MLA Liu, Bailing,et al."Adsorption behavior of protein onto siloxane microspheres".Applied surface science 252.22(2006):7830-7836.

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来源:中国科学院大学

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