Adsorption behavior of protein onto siloxane microspheres
文献类型:期刊论文
作者 | Liu, Bailing; Cao, Shunsheng; Deng, Xiaobo; Li, Songjun; Luo, Rong |
刊名 | Applied surface science
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出版日期 | 2006-09-15 |
卷号 | 252期号:22页码:7830-7836 |
关键词 | Siloxane microspheres Bovine serum albumin (bsa) Protein adsorption |
ISSN号 | 0169-4332 |
DOI | 10.1016/j.apsusc.2005.09.058 |
通讯作者 | Liu, bailing(blliuchem@hotmail.com) |
英文摘要 | The siloxane microspheres with core-shell structure (pmma/pmps) (mma, methyl methacrylate; mps, 3-methacryloxypropyl-trimethoxysilane) have been prepared by dispersion polymerization as described in our previous work. in this paper, the developed poly(mma-mps) microspheres, as a carrier, are used to investigate the adsorption behavior of bovine serum albumin (bsa) on them. the langmuir and freundlich models have been applied to describe the adsorption behavior. the experimental results indicated that the presence of pmps evidently increases the adsorption rate and the amount of protein, and it also influences the interaction of bsa molecules. the adsorption of bsa on the poly(mma-mps) microspheres seems to be sensitive to ph and ionic strength. the fittings curves from langmuir and freundlich models showed that the adsorption was actually more complicated than ideal situation because one or more interactions were involved in the process. for understanding the electronic contribution, the zeta potential was used to measure the reactive system before and after protein adsorption. (c) 2005 elsevier b.v. all rights reserved. |
WOS关键词 | BOVINE SERUM-ALBUMIN ; POLYMERIC BIOMATERIALS ; SURFACE MODIFICATION ; IONIC-STRENGTH ; IMMOBILIZATION ; ISOTHERMS ; PARTICLES ; HYDROXYAPATITE ; PROPERTY ; SUPPORTS |
WOS研究方向 | Chemistry ; Materials Science ; Physics |
WOS类目 | Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter |
语种 | 英语 |
WOS记录号 | WOS:000240792100015 |
出版者 | ELSEVIER SCIENCE BV |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2379120 |
专题 | 中国科学院大学 |
通讯作者 | Liu, Bailing |
作者单位 | Chinese Acad Sci, Grad Sch, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Bailing,Cao, Shunsheng,Deng, Xiaobo,et al. Adsorption behavior of protein onto siloxane microspheres[J]. Applied surface science,2006,252(22):7830-7836. |
APA | Liu, Bailing,Cao, Shunsheng,Deng, Xiaobo,Li, Songjun,&Luo, Rong.(2006).Adsorption behavior of protein onto siloxane microspheres.Applied surface science,252(22),7830-7836. |
MLA | Liu, Bailing,et al."Adsorption behavior of protein onto siloxane microspheres".Applied surface science 252.22(2006):7830-7836. |
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来源:中国科学院大学
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