The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains
文献类型：期刊论文
| 作者 | Wang, XingShen; Wang, DongLiang; Zhao, Jing; Qu, MeiHua; Zhou, XiaoHong; He, HaiJin; He, RongQiao |
| 刊名 | Protein and peptide letters
 |
| 出版日期 | 2006 |
| 卷号 | 13期号:7页码:679-685 |
| 关键词 | Neuronal tau Rna Non-sequence-specific rna-binding Electrostatic interaction Proline rich domain Microtubule binding domain |
| ISSN号 | 0929-8665 |
| 通讯作者 | He, rongqiao(herq@sun5.ibp.ac.cn) |
| 英文摘要 | Neuronal tau, through its proline-rich domain and the microtubule binding domain, binds to rna nonsequence-specifically via electrostatic interaction. this binding inhibits the activity of tau. tau and rna were also found to co-localize in sh-sy5y cells suggesting that rna has opportunities to interact with tau in cells. |
| WOS关键词 | PAIRED HELICAL FILAMENTS ; NEUROFIBRILLARY TANGLES ; ALZHEIMERS-DISEASE ; TUBULIN ; BRAIN ; AGGREGATION ; INHIBITION ; POLYANIONS ; EXPRESSION ; ISOFORMS |
| WOS研究方向 | Biochemistry & Molecular Biology |
| WOS类目 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000238786500006 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2379680 |
| 专题 | 中国科学院大学 |
| 通讯作者 | He, RongQiao |
| 作者单位 | 1.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, XingShen,Wang, DongLiang,Zhao, Jing,et al. The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains[J]. Protein and peptide letters,2006,13(7):679-685. |
| APA | Wang, XingShen.,Wang, DongLiang.,Zhao, Jing.,Qu, MeiHua.,Zhou, XiaoHong.,...&He, RongQiao.(2006).The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains.Protein and peptide letters,13(7),679-685. |
| MLA | Wang, XingShen,et al."The proline-rich domain and the microtubule binding domain of protein tau acting as rna binding domains".Protein and peptide letters 13.7(2006):679-685. |
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来源：中国科学院大学
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