Assessing the quality of rcts on the effect beta-elemene, one ingredient of a chinese herb, against malignant tumors
文献类型：期刊论文
| 作者 | Peng, XX; Zhao, YL; Liang, XY; Wu, LJ; Cui, SQ; Guo, AM; Wang, W |
| 刊名 | Contemporary clinical trials
 |
| 出版日期 | 2006-02-01 |
| 卷号 | 27期号:1页码:70-82 |
| 关键词 | Chinese herbs medicine Elemene injections Rcts Evaluation of quality |
| ISSN号 | 1551-7144 |
| DOI | 10.1016/j.cct.2005.07.002 |
| 通讯作者 | Wang, w() |
| 英文摘要 | Objective: to evaluate the quality of randomized controlled trials (rcts) for elemene injections, one ingredient of chinese herb curcuma wenyujin, for malignant tumors widely used in clinical practice in china. methods: we used a systematic sample of 127 reports of rcts that used elemene injections as an intervention. the quality of each report was assessed using the number of consolidated standards for reporting of trials (consort) checklist items included, the frequency of allocation concealment and a 5-point quality assessment instrument (jadad). results: 69.44% of the consort checklist items was included in the reports. only 2 (1.57%) rcts reported allocation concealment by sealed envelopes. 123 (96.85%) reports described baseline demographic and clinical characteristics of each group. but only 5 (3.94%) of 127 rcts reported statistics analysis results of baseline data. none of the reports stated in the methods section that intention-to-treat (itt) analysis was used, although 111 (87.40%) reports described the number of participants (denominator) in each group included in each analysis. information regarding adverse events was reported in 83.46% of the rcts. however the quality of reports were low as assessed by the jadad scale. conclusions: the methodological quality of rcts of elemene injection against malignant tumors was low. therefore, the effect of elemene injection being used in clinical settings needs to be confirmed by further rcts. |
| WOS关键词 | RANDOMIZED-TRIALS ; CONSORT STATEMENT ; CLINICAL-TRIALS ; CELL-CYCLE ; ARREST |
| WOS研究方向 | Research & Experimental Medicine ; Pharmacology & Pharmacy |
| WOS类目 | Medicine, Research & Experimental ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000234187400007 |
| 出版者 | ELSEVIER SCIENCE INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2379882 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, W |
| 作者单位 | 1.Capital Univ Med Sci, Sch Publ Hlth & Family Med, Beijing 100054, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Edith Cowan Univ, Ctr Human Genet, Perth, WA 6027, Australia |
| 推荐引用方式 GB/T 7714 | Peng, XX,Zhao, YL,Liang, XY,et al. Assessing the quality of rcts on the effect beta-elemene, one ingredient of a chinese herb, against malignant tumors[J]. Contemporary clinical trials,2006,27(1):70-82. |
| APA | Peng, XX.,Zhao, YL.,Liang, XY.,Wu, LJ.,Cui, SQ.,...&Wang, W.(2006).Assessing the quality of rcts on the effect beta-elemene, one ingredient of a chinese herb, against malignant tumors.Contemporary clinical trials,27(1),70-82. |
| MLA | Peng, XX,et al."Assessing the quality of rcts on the effect beta-elemene, one ingredient of a chinese herb, against malignant tumors".Contemporary clinical trials 27.1(2006):70-82. |
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来源：中国科学院大学
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