Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction
文献类型：期刊论文
| 作者 | Wang, Yun1,2,3; Kong, Liang4; Lei, Xiaoyuan1; Hu, Lianghai1; Zou, Hanfa1; Welbeck, Ed5; Bligh, S. W. Annie5; Wang, Zhengtao2,3 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2009-03-13 |
| 卷号 | 1216期号:11页码:2185-2191 |
| 关键词 | Comprehensive two-dimensional chromatography ILC column Biological finger printing analysis Longdan Xiegan Decoction Traditional Chinese medicine |
| ISSN号 | 0021-9673 |
| 产权排序 | 2;1 |
| 通讯作者 | 邹汉法 ; zhengtao wang |
| 英文摘要 | a comprehensive two-dimensional hplc system with an immobilized liposome chromatography (ilc) column in conjunction with all rp column (in tandem) was developed for the screening and analysis of the membrane-permeable compounds in a traditional chinese medicine prescription longdan xiegan decoction (lxd). more than 50 components in lxd were resolved using the developed separation system. eight flavonoids and two iridoids were identified interacting with the ilc column: a system that mimics biomembranes. the results show that the developed comprehensive two-dimensional chromatography system can be used for identifying membrane permeable natural products in complex matrixes such as extracts of traditional chinese medicine prescriptions. (c) 2008 published by elsevier b.v. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | tandem mass-spectrometry ; protein ; identification ; membrane ; hplc ; prescription ; digestion |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000264226500028 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/101569]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Minist Educat, Key Lab Standuidizat Chinese Med, Shanghai 201210, Peoples R China 3.China Pharmaceut Univ, Dept Pharmacognosy, Nanjing 210038, Peoples R China 4.Dalian Fisheries Univ, Coll Marine Environm Engn, Dalian 116023, Peoples R China 5.London Metropolitan Univ, Inst Hlth Res & Policy, London N7 8D8, England |
| 推荐引用方式 GB/T 7714 | Wang, Yun,Kong, Liang,Lei, Xiaoyuan,et al. Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction[J]. journal of chromatography a,2009,1216(11):2185-2191. |
| APA | Wang, Yun.,Kong, Liang.,Lei, Xiaoyuan.,Hu, Lianghai.,Zou, Hanfa.,...&Wang, Zhengtao.(2009).Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction.journal of chromatography a,1216(11),2185-2191. |
| MLA | Wang, Yun,et al."Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction".journal of chromatography a 1216.11(2009):2185-2191. |
入库方式： OAI收割
来源：大连化学物理研究所
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