CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes
文献类型：期刊论文
| 作者 | Liu, H. -X.1,2; Hu, Y.1; Liu, Y.1; He, Y. -Q.3; Li, W.1,2; Yang, L.1 |
| 刊名 | xenobiotica
 |
| 出版日期 | 2009 |
| 卷号 | 39期号:9页码:672-679 |
| 关键词 | Paeonol cytochrome P450 O-demethylated metabolite |
| 产权排序 | 1;1 |
| 通讯作者 | 杨凌 |
| 英文摘要 | 1. paeonol, the primary active component of a traditional chinese medicine moutan cortex, has a wide range of pharmacological activities. in the present study, the metabolism of paeonol by cytochrome p450s (cyps) was investigated in human liver microsomes. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | pharmacology & pharmacy ; toxicology |
| 研究领域[WOS] | pharmacology & pharmacy ; toxicology |
| 关键词[WOS] | nf-kappa-b ; cytochrome-p450 ; metabolism ; expression ; induction ; enzymes ; polymorphism ; variability ; inhibition ; mechanism |
| 收录类别 | SCI |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000270090800005 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/101787]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Shanghai Univ Tradit Chinese Med, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, H. -X.,Hu, Y.,Liu, Y.,et al. CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes[J]. xenobiotica,2009,39(9):672-679. |
| APA | Liu, H. -X.,Hu, Y.,Liu, Y.,He, Y. -Q.,Li, W.,&Yang, L..(2009).CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes.xenobiotica,39(9),672-679. |
| MLA | Liu, H. -X.,et al."CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes".xenobiotica 39.9(2009):672-679. |
入库方式： OAI收割
来源：大连化学物理研究所
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