Formation of nano-hydroxyapatite in gelatin droplets and the resulting porous composite microspheres
文献类型:期刊论文
作者 | Teng, Shuhua; Chen, Lijuan; Guo, Yanchuan; Shi, Jingjing |
刊名 | Journal of inorganic biochemistry
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出版日期 | 2007-04-01 |
卷号 | 101期号:4页码:686-691 |
关键词 | Nano-hydroxyapatite Gelatin Composite microspheres One-pot Emulsion |
ISSN号 | 0162-0134 |
DOI | 10.1016/j.jinorgbio.2006.11.018 |
通讯作者 | Chen, lijuan(chenlijuan@mail.ipc.ac.cn) |
英文摘要 | A one-pot strategy was first presented in this paper to synthesize gelatin/hydroxyapatite (hap) composite microspheres in a water-in-oil (w/o) emulsion. using gelatin droplets as microreactors and colloid protective medium, needle-like nano-hap crystals (5 nm x 60-100 nm) in form of clusters were homogeneously and orderly precipitated within gelatin matrix. the results of scanning electron microscopy (sem) revealed that the as-prepared microspheres with an average diameter of 7.5 mu m displayed a narrow particle size distribution, a high dispersity and a naturally porous structure. this microsphere material is expected to have a great potential for both controlled drug release and faster bone in-growth in bone tissue engineering. (c) 2006 elsevier inc. all rights reserved. |
WOS关键词 | DRUG-RELEASE ; BONE ; COLLAGEN ; NANOCOMPOSITES ; SCAFFOLDS ; DELIVERY ; RABBIT ; NANOPARTICLES ; NETWORK ; POWDER |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
WOS类目 | Biochemistry & Molecular Biology ; Chemistry, Inorganic & Nuclear |
语种 | 英语 |
WOS记录号 | WOS:000245616000016 |
出版者 | ELSEVIER SCIENCE INC |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2381741 |
专题 | 中国科学院大学 |
通讯作者 | Chen, Lijuan |
作者单位 | 1.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Teng, Shuhua,Chen, Lijuan,Guo, Yanchuan,et al. Formation of nano-hydroxyapatite in gelatin droplets and the resulting porous composite microspheres[J]. Journal of inorganic biochemistry,2007,101(4):686-691. |
APA | Teng, Shuhua,Chen, Lijuan,Guo, Yanchuan,&Shi, Jingjing.(2007).Formation of nano-hydroxyapatite in gelatin droplets and the resulting porous composite microspheres.Journal of inorganic biochemistry,101(4),686-691. |
MLA | Teng, Shuhua,et al."Formation of nano-hydroxyapatite in gelatin droplets and the resulting porous composite microspheres".Journal of inorganic biochemistry 101.4(2007):686-691. |
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来源:中国科学院大学
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