Direct chiral separation of four indole derivatives by high performance liquid chromatography with chiral stationary phase
文献类型：期刊论文
| 作者 | Li Xiu-Juan; Zhao Liang; Ming Yong-Fei; Peng Xian-Zhi; Zhou Yong-Zhang; Chen Li-Ren |
| 刊名 | Chinese journal of analytical chemistry
 |
| 出版日期 | 2007-04-01 |
| 卷号 | 35期号:4页码:515-519 |
| 关键词 | High performance liquid chromatography Enantioseparation Indole derivatives Cellulose-tris (3 5-dimethylphenyl carbamate) chiral stationary phase |
| ISSN号 | 0253-3820 |
| 通讯作者 | Zhou yong-zhang(eeszhou@zsu.edu.cn) |
| 英文摘要 | A chiral stationary phase (csp) was prepared by coating cellulose tris (3,5-dimethylphenyl carbamate) (cdmpc) onto lab-made aminopropylated spherical silica gel. four new synthesised chiral indole derivatives were directly resolved on the cdmpc-csp by normal-phase system. the influences of structure and concentration of the alcohol in mobile phases on the separation of indole derivatives by high performance liquid chromatography with csp were investigated for the optimization of chromatographic conditions. butanol ethanol and ethanol were appropriate for the separation of sample ii sample iii and sample iv as the modifiers respectively, while the mixture of ethanol and propanol was suitable for sample i. under the optimal conditions, excellent enantioseparation was achieved and the enantiomer excess(e.e.) values of indole derivatives were determined. the satisfactory results indicated that the method is ideal for the separation of indole derivatives. |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000246717800010 |
| 出版者 | SCIENCE CHINA PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2382101 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhou Yong-Zhang |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Geochem, Guangzhou 510640, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Xiu-Juan,Zhao Liang,Ming Yong-Fei,et al. Direct chiral separation of four indole derivatives by high performance liquid chromatography with chiral stationary phase[J]. Chinese journal of analytical chemistry,2007,35(4):515-519. |
| APA | Li Xiu-Juan,Zhao Liang,Ming Yong-Fei,Peng Xian-Zhi,Zhou Yong-Zhang,&Chen Li-Ren.(2007).Direct chiral separation of four indole derivatives by high performance liquid chromatography with chiral stationary phase.Chinese journal of analytical chemistry,35(4),515-519. |
| MLA | Li Xiu-Juan,et al."Direct chiral separation of four indole derivatives by high performance liquid chromatography with chiral stationary phase".Chinese journal of analytical chemistry 35.4(2007):515-519. |
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来源：中国科学院大学
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